ArticleBioprocess and biosystems engineering2025
Eco-friendly synthesis and biomedical potential of zinc oxide nanoparticles using Mentha piperita aqueous extract: comparative analysis with chemically synthesized and commercial nanoparticles.
Article in Bioprocess and biosystems engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Biocatalytic and biogenic pathways for sustainable nanoparticle synthesis: mechanisms, monitoring, and circular bioeconomy integration.Bioprocess and biosystems engineering · 2026Review
- Article
- Green synthesis of ZnO nanoparticles from melon peel and mint stem: antibacterial, antioxidant, and dye degradation potential.Scientific reports · 2026Article
- Analysis of Phytochemicals and Functional Groups From Aqueous Extracts of Malawian Vernonia amygdalina Del. for Potential Applications.Chemistry & biodiversity · 2026Article
- Article
- Phytochemical Composition and Antioxidant Activity of Traditional Plant Extracts with Biocidal Effects and Soil-Enhancing Potential.Antioxidants (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Phytosynthesis of zinc oxide nanoparticles (ZnO NPs) using Mentha piperita extract offers a sustainable alternative for biomedical applications. This study investigates the synthesis, characterization, and biological properties of biosynthesized ZnO (ZnO Bio NPs) compared to chemically synthesized (ZnO Chem NPs) and commercial ZnO (ZnO Commercial NPs). We explored how peppermint's phytochemicals influence ZnO NP synthesis and biological interactions. Peppermint-derived phytochemicals act as reducing and stabilizing agents while providing antioxidant and anticarcinogenic benefits, potentially enhancing ZnO Bio NPs' therapeutic effects. Our findings reveal that ZnO Bio NPs exhibit superior stability and bioactivity due to plant-based capping agents. ZnO Bio NPs inhibited 52% of DPPH radicals at 15.63 µg/mL, outperforming ZnO Chem and Commercial NPs. In hemocompatibility studies, ZnO Bio NPs showed minimal hemolysis, both with and without protein corona (albumin and fibrinogen), ensuring safer blood interactions. Cytotoxicity assays demonstrated that ZnO Bio NPs had an IC50 of 49.91 µg/mL in human fibroblasts, threefold less cytotoxic than ZnO Commercial NPs. These results highlight the potential of peppermint-extract-based ZnO NPs for biomedical applications, offering lower cytotoxicity and greater biocompatibility while providing an eco-friendly alternative to conventional synthesis methods.
Indexed as
Identifiers
40411556What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.