Evidence map›Paper›PMID 40411415›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

A Supramolecular Material for Controlling Kiwifruit Bacterial Canker.

Xile Deng, Qiang Bian, Mingqing Zhou, Le Xie, Jichuan Zhang, Tianqi Liu, Yizhuo Zhang, Li Zhang, Jiaheng Zhang, Lianyang Bai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A GAPlant communications · 2026
    Article
  2. Article
  3. A Supramolecular Material for Controlling Kiwifruit Bacterial Canker.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xile DengHunan Academy of Agricultural Sciences, Changsha, 410125, China.
Qiang BianNational Pesticide Engineering Research Center (Tianjin), College of Chemistry, Nankai University, Tianjin, 300071, China.
Mingqing ZhouDepartment of Chemistry, College of Sciences, Northeastern University, Shenyang, 110819, China.
Le XieDepartment of Neurology, Hunan Academy of Chinese Medicine Affiliated Hospital (Hunan Hospital of Integrated Traditional Chinese and Western Medicine), Changsha, 410006, China.
Jichuan ZhangSchool of Material Sciences and Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen, 518055, China.
Tianqi LiuSchool of Material Sciences and Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen, 518055, China.
Yizhuo ZhangDepartment of Microbiology, College of Life Sciences, Nankai University, Tianjin, 300071, China.
Li ZhangDepartment of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China.
Jiaheng ZhangSchool of Material Sciences and Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen, 518055, China.ORCID https://orcid.org/0000-0002-2377-9796
Lianyang BaiHunan Academy of Agricultural Sciences, Changsha, 410125, China.

Funding

National Natural Science Foundation of China 22177132Science and Technology Innovation Program of Hunan Province 2023RC3208Science and Technology Innovation Program of Hunan Province 2023RC3215Shenzhen Science and Technology Innovation Committee GXWD20201230155427003-20200821181245001Shenzhen Science and Technology Innovation Committee GXWD2020123015542700320200821181809 001Shenzhen Science and Technology Innovation Committee ZX20200151
6 · The paper itself

Abstract

Kiwifruit, a nutritious fruit consumed globally, is affected by kiwifruit bacterial canker (KBC) caused by Pseudomonas syringae pv. actinidiae (Psa), which is a major biotic stress that adversely impacts its cultivation and production. KBC control is still challenging owing to the evolution of resistant populations of Psa, the environmental risks associated with copper bactericides, and lack of effective bactericides. Therefore, to develop novel and efficient bactericides against Psa, a matrine (MT)-5-methylsalicylic acid (5-OMESA) salt (MOS) is synthesized and its antibacterial activity is analyzed. The newly synthesized compound is more antibacterial against Psa than the commercial bactericide thiazole copper (TC). MOS significantly disrupts the membrane structure of Psa and penetrates the cells more efficiently. In addition, it has high affinities to the Psa FtsZ protein and DNA helicase, which probably contribute to its bactericidal activity. Subsequently, the encapsulation of MOS into a supramolecular nanocarrier hydroxypropyl-β-cyclodextrin (HPCD) and the fabrication of a nano formulation (MOS@HPCD) result in superior solubility, penetration, foliar deposition and wettability, sustained release, and prolonged protection against Psa. The in vitro and in vivo control efficiencies of MOS@HPCD against Psa are markedly enhanced compared to those of MOS. This study proposes a promising supramolecular material to control KBC.

Indexed as

ActinidiaAnti-Bacterial AgentsPlant DiseasesPseudomonas syringaeFruitAnti-Bacterial Agentsbactericidal activitykiwifruit bacterial canker (KBC)molecular simulationsnano pesticidesupramolecular nanocarrier

Identifiers

PMID40411415
PMCPMC12376517

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.