Evidence map›Paper›PMID 40411413›Full record

ArticleProtein science : a publication of the Protein Society2025

Project automation in CCP4 Cloud: Enabling customization and high-throughput efficiency.

Eugene Krissinel, Maria Fando, Oleg Kovalevskiy, Ronan Keegan, Jools Wills, Andrey Lebedev, Ville Uski, Charles Ballard

Abstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Project automation in CCP4 Cloud: Enabling customization and high-throughput efficiency.Protein science : a publication of the Protein Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eugene KrissinelResearch Complex at Harwell, Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.ORCID 0000-0003-1267-7185
Maria FandoResearch Complex at Harwell, Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.
Oleg KovalevskiyResearch Complex at Harwell, Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.
Ronan KeeganResearch Complex at Harwell, Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.
Jools WillsResearch Complex at Harwell, Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.
Andrey LebedevResearch Complex at Harwell, Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.
Ville UskiResearch Complex at Harwell, Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.
Charles BallardResearch Complex at Harwell, Scientific Computing Department, Science and Technology Facilities Council, Harwell, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/L007037/1Collaborative Computational Project Number 4 UK
6 · The paper itself

Abstract

The rapid advancement of automatic structure solution methods, driven by the availability of high-quality predicted structures from AlphaFold and the growing adoption of multi-crystal and serial experiments, has created a pressing need for streamlining routine operations, automating structure solution projects, and efficiently handling large volumes of data. Modern software solutions must be both robust and user-friendly, supporting manual workflows while enabling high-throughput operations to keep pace with the high data collection rates of modern beamlines. Here, we present new developments in CCP4 Cloud that address these challenges by providing predefined and customizable automatic workflows, which can be seamlessly integrated with experimental facilities, offering a powerful solution for modern macromolecular crystallography. CCP4 Cloud is available as a public service at https://cloud.ccp4.ac.uk.

Indexed as

Cloud ComputingProteinsSoftwareAutomationCrystallography, X-RayProtein ConformationProteinsautomatic workflowscomputational cloudmacromolecular crystallographystructure solution

Identifiers

PMID40411413
PMCPMC12102756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.