Evidence map›Paper›PMID 40411365›Full record

ArticleMagnetic resonance in medicine2025

Multi-compartment metabolic assessment of the kidneys by co-hyperpolarized

Cornelius von Morze, Ashley Shaw, Kooresh I Shoghi, Tyler Blazey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cornelius von MorzeMallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-3992-1793
Ashley ShawMallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA.
Kooresh I ShoghiMallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA.
Tyler BlazeyMallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0002-3402-0654

Funding

WASHINGTON UNIVERSITY CO-CLINICAL IMAGING RESEARCH RESOURCEU24CA209837 · NCI · WASHINGTON UNIVERSITY · PI Li Ding, Shunqiang Li · 2017 to 2026
$6.3M
Hyperpolarized 13C MRI of renal mitochondrial dysfunctionR21DK131358 · NIDDK · WASHINGTON UNIVERSITY · PI VON MORZE, CORNELIUS · 2022 to 2023
$430k
NCI NIH HHS U24 CA209837NIDDK NIH HHS R21 DK131358NIDDK NIH HHS R21DK131358
6 · The paper itself

Abstract

purposeThe purpose of this study was to show that hyperpolarized (HP) carbon-13 (

methods[1-

resultsMetabolic conversions of both co-HP substrates showed large shifts in diabetic kidney with chronic hyperglycemia. Production of both HP [1-

conclusionNoninvasive

Indexed as

KidneyMagnetic Resonance ImagingAcetoacetatesAnimalsCarbon IsotopesMalePyruvic AcidRatsRats, Sprague-DawleyAcetoacetatesacetoacetic acidCarbon-13Carbon IsotopesPyruvic Aciddiabetesdynamic nuclear polarizationkidney

Identifiers

PMID40411365
PMCPMC12204795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.