Evidence map›Paper›PMID 40411306›Full record

ArticleHuman vaccines & immunotherapeutics2025

Antibody-dependent enhancement of SARS-CoV-2, the impact of variants and vaccination.

Swapna Thomas, Maria K Smatti, Hebah Atef Mohammad AlKhatib, Yaman Tayyar, Muna Nizar, Hadeel T Zedan, Allal Ouhtit, Asmaa A Althani, Gheyath K Nasrallah, Hadi M Yassine

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Swapna ThomasBiomedical Research Center, QU Health, Qatar University, Doha, Qatar.
Maria K SmattiBiomedical Research Center, QU Health, Qatar University, Doha, Qatar.
Hebah Atef Mohammad AlKhatibBiomedical Research Center, QU Health, Qatar University, Doha, Qatar.
Yaman TayyarBiomedical Research Center, QU Health, Qatar University, Doha, Qatar.
Muna NizarBiomedical Research Center, QU Health, Qatar University, Doha, Qatar.
Hadeel T ZedanBiomedical Research Center, QU Health, Qatar University, Doha, Qatar.
Allal OuhtitDepartment of Biological and Environmental Sciences, College of Arts and Sciences, Qatar University, Doha, Qatar.
Asmaa A AlthaniBiomedical Research Center, QU Health, Qatar University, Doha, Qatar.
Gheyath K NasrallahBiomedical Research Center, QU Health, Qatar University, Doha, Qatar.
Hadi M YassineBiomedical Research Center, QU Health, Qatar University, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study characterized antibody-dependent enhancement (ADE) in serum samples from individuals exposed to SARS-CoV-2 via infection or vaccination and evaluated its association with SARS-CoV-2 variants (Wuhan and Omicron), MERS-CoV, and NL63. ADE assays were performed on sera from SARS-CoV-2-infected patients (

Indexed as

Antibodies, ViralAntibody-Dependent EnhancementCOVID-19COVID-19 VaccinesSARS-CoV-2AdultAgedAntibodies, NeutralizingComplement ActivationFemaleHumansImmunoglobulin GMaleMiddle AgedMiddle East Respiratory Syndrome CoronavirusmRNA VaccinesAntibodies, NeutralizingAntibodies, ViralCOVID-19 VaccinesImmunoglobulin GmRNA VaccinesADEimmunologySARS-CoV2variantsVirology

Identifiers

PMID40411306
PMCPMC12118418

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.