ReviewJournal of internal medicine2025
Implementing early detection of cognitive impairment in primary care to improve care for older adults.
Review in Journal of internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Reliability, Validity, and Diagnostic Accuracy of the Persian Six-Item Cognitive Impairment Test (6-CIT) in Older Adult Outpatients.Brain and behavior · 2026Article
- Neurons Die Not by One Hit, but by Signaling Convergence.Molecular neurobiology · 2026Review
- Deep Learning-Derived Retinal Age Detects Cognitive Impairment.Ophthalmology science · 2026Article
- Clinical implementation of digital cognitive assessments - recommendations from Global CEO Initiative on Alzheimer's Disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Bridging the diagnostic gap: Expanding dementia care navigation for timely diagnosis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Digital speech-based markers to advance prognosis in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Healthcare utilization and morbidity preceding a dementia classification: the Atherosclerosis Risk in Communities (ARIC) study.BMC health services research · 2026Article
- Undiagnosed dementia and mortality among older adults in the United States and Brazil: A cross-national cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- The Davos Alzheimer's Collaborative Healthcare System Preparedness US Early Detection of Cognitive Impairment Program in primary care: Methodology.BMC primary care · 2026Article
- System changes to empower primary care in Alzheimer's disease detection and care.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Addressing Frailty in the Emergency Department: Early Outcomes of a Geriatric Rapid Access Clinic.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026Article
- Emergency Department Utilisation and Related Costs in People With and Without Dementia in Their Last Years of Life.Emergency medicine Australasia : EMA · 2026Article
- Target product profiles for treatments to delay or prevent symptomatic Alzheimer's disease.Nature medicine · 2026Review
- Validation of the brief assessment of impaired cognition (BASIC) and brief assessment of impaired cognition questionnaire (BASIC-Q) in Italy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Early screening of mild cognitive impairment based on eye-tracking technology: a cross-sectional study.Aging clinical and experimental research · 2026Article
- Semi-Supervised Clustering for Identification of MCI and Dementia Cohorts with a Brief Digital Cognitive Assessment.Research square · 2026Article
- Cognitive decline, and quality of life: evidence from community-dwelling older adults in the United Arab Emirates.Frontiers in aging · 2026Article
- Development and Internal Validation of a Machine Learning-Based Classification Model for Identifying Cognitive Frailty in Older Inpatients with Type 2 Diabetes Mellitus.Clinical interventions in aging · 2026Article
- Burden of geriatric and cognitive disorders and the impact of integrated care models on morbidity, functional decline, and health service utilization among older adults.Frontiers in medicine · 2026Article
- TriFusion-ADFormer: a deep learning framework for early Alzheimer's disease detection using MRI and cognitive metrics.Frontiers in artificial intelligence · 2026Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Primary care is the ideal setting for early detection of mild cognitive impairment (MCI) and Alzheimer's disease and related dementias (ADRD), as it serves as the primary point of care for most older adults. With the growing aging population, reliance on specialists for detection and diagnosis is unsustainable, highlighting the need for primary care-led assessment. Recent research findings on successful brain health prevention strategies, AD diagnostic tools, and anti-amyloid treatments empower primary care to play a central role in early detection and intervention. Primary care-focused resources are being developed, including tools for cognitive assessments and materials designed to educate patients about brain health and initiate discussions on lifestyle modifications, thereby making early detection more feasible and efficient. Identifying risk factors early enables providers to implement interventions that can slow cognitive decline and improve outcomes for patients and caregivers. If left undetected and unmanaged, MCI and ADRD can lead to worse outcomes, including increased falls, hospitalizations, financial vulnerability, and caregiver stress. Early detection enables the identification of reversible causes of cognitive impairment, supports the management of comorbidities worsened by cognitive decline, mitigates safety risks, and can preserve quality of life. Importantly, primary care is essential for addressing ADRD-related health disparities that disproportionately affect racial minorities, rural populations, and those of lower socioeconomic status. With a focus on the United States healthcare system, this perspective addresses how implementing early detection practices into primary care can improve outcomes for patients and caregivers, reduce societal burdens, and promote health equity in ADRD care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.