Evidence map›Paper›PMID 40410874›Full record

ReviewJournal of medical case reports2025

Microapical surgery of a periapical cyst caused by apical ramification: a case report and review of the literature.

Liyun Bai, Na Hu, Qin Yang, Dongquan Pu, Xiaoqian Feng, Yiyun Yue, Weiwei Xiao, Rui Liu, Li Liu, Xia Zhou

Abstract readCase ReportsReview
In one paragraph

Review in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liyun Bai *Department of Stomatology, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.
Na Hu *The Affiliated Stomatological Hospital of Chongqing Medical University, Chongqing, 401147, China.
Qin YangDepartment of Stomatology, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.
Dongquan PuOti Road Stomatological Clinic of Chongqing Oumu Dental Clinic Management Co., Ltd, Chongqing, 400042, People's Republic of China.
Xiaoqian FengDepartment of Stomatology, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.
Yiyun YueDepartment of Stomatology, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.
Weiwei XiaoDepartment of Stomatology, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China.
Rui LiuDepartment of Stomatology, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China. liurui123@tmmu.edu.cn.
Li LiuDepartment of Stomatology, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China. rainbow@tmmu.edu.cn.
Xia ZhouDepartment of Stomatology, Daping Hospital, Army Medical University, Chongqing, 400042, People's Republic of China. dentistzx@tmmu.edu.cn.

Funding

Natural Science Foundation of Xinjiang XZ202501ZR0050the Micro-course Project of Postgraduate Education of Army Medical University Y2025W17the Natural Science Foundation of Shigatse Region RKZ2025ZR-002the Postgraduate Education Research Project of Army Medical University 2023yjsB15
6 · The paper itself

Abstract

backgroundThe destruction of tooth apical bone mainly comes from odontogenic apical cysts caused by pulp necrosis, chronic inflammation, or trauma. Some affected teeth can be cured by modern root canal treatment or non-surgical retreatment, but some affected teeth do not heal after treatment. Apical surgery should be considered when root canal therapy has failed, root canal retreatment through the crown channel is difficult, or true cysts are present. This article explores the use of microapical surgery to treat a periapical cyst caused by apical ramification, emphasizing a minimal surgical approach for this lesion. CASE PRESENTATION: A 47-year-old female (Han nationality) presented with a chief complaint of recurrent buccal mucosal fistula in their maxillary posterior teeth for 1 year. Clinical examination revealed a porcelain-fused-metal crown of the maxilla of the left second premolar (tooth 25) and buccal mucosa fistula. X-ray assessment showed a high-density shadow in the root canal and low-density transmission from the root apex to the middle third of distal root surface. Microscopic apical surgery was performed under local anesthesia. The apical ramification was exposed and a root apex of 3 mm was cut off. Then the apical foramen of buccal root canal, palatal root canal, and apical ramification were filled retrogradely with mineral trioxide aggregate, and finally sewn up. Follow-up X-ray at postoperative 12 months and 24 months showed that the bone density of the root apex and distal root surface was higher compared with the values measured immediately after operation. There were no clinical symptoms, and normal mucosa.

conclusionThe patient presented with a recurrent buccal mucosal fistula in the maxillary left second premolar. Microscopic apical surgery was performed under local anesthesia. After minimally invasive surgery, apical resection, inverted preparation, and mineral trioxide aggregate treatment, at postoperative 24 months, the outcome was satisfactory, with recovered apical bone, normal mucosa, and no clinical symptoms. For periapical cysts, X-ray and cone-beam computed tomography images should be read carefully before the operation. The semicircular low-density transmission image around the apical sidewall indicates the apical ramification, and that root canal treatment or microapical surgery should be performed. The operating microscope enhances visibility and provides the surgeon with a better understanding of canal anatomy, a better surgical view, and the ability to undertake more complex but predictable apical resection techniques.

Indexed as

Radicular CystTooth ApexFemaleHumansMaxillaMiddle AgedTreatment OutcomeApical ramificationMicroapical surgeryPeriapical cyst

Identifiers

PMID40410874
PMCPMC12100992

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.