Evidence map›Paper›PMID 40410713›Full record

ArticleBMC medical education2025

Assessing ChatGPT-4's performance on the US prosthodontic exam: impact of fine-tuning and contextual prompting vs. base knowledge, a cross-sectional study.

Mahmood Dashti, Farshad Khosraviani, Tara Azimi, Delband Hefzi, Shohreh Ghasemi, Amir Fahimipour, Niusha Zare, Zohaib Khurshid, Syed Rashid Habib

Abstract read
In one paragraph

Article in BMC medical education, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Preliminary Evaluation of Large Language Models in Kennedy Classification and Removable Partial Denture Planning: An In Silico Study.Medical science monitor : international medical journal of experimental and clinical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mahmood DashtiDentofacial Deformities Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tajrish, District 1, Daneshjou Blvd, Tehran, Tehran Province, Iran. dashti.mahmood72@gmail.com.
Farshad KhosravianiUCLA School of Dentistry, Los Angeles, CA, USA.
Tara AzimiOrofacial Pain and Disfunction, UCLA School of Dentistry, Los Angeles, CA, USA.
Delband HefziSchool of Dentistry, Tehran University of Medical Science, Tehran, Iran.
Shohreh GhasemiTrauma and Craniofacial Reconstruction, Queen Mary College, London, England.
Amir FahimipourDiscipline of Oral Surgery, Medicine and Diagnostics, Faculty of Medicine and Health, Westmead Hospital, The University of Sydney, Sydney, NSW, 2145, Australia.
Niusha ZareDepartment of Operative Dentistry, University of Southern California, Los Angeles, USA.
Zohaib KhurshidCenter of Excellence for Regenerative Dentistry, Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, Bangkok, 10330, Thailand.
Syed Rashid HabibDepartment of Prosthetic Dental Sciences, College of Dentistry, King Saud University, P. O. Box 60169, King Abdullah Road, 11545, Riyadh, Saudi Arabia. syhabib@ksu.edu.sa.

Funding

King Faisal University RSPD2025R950
6 · The paper itself

Abstract

backgroundArtificial intelligence (AI), such as ChatGPT-4 from OpenAI, has the potential to transform medical education and assessment. However, its effectiveness in specialized fields like prosthodontics, especially when comparing base to fine-tuned models, remains underexplored. This study evaluates the performance of ChatGPT-4 on the US National Prosthodontic Resident Mock Exam in its base form and after fine-tuning. The aim is to determine whether fine-tuning improves the AI's accuracy in answering specialized questions.

methodsAn official sample questions from the 2021 US National Prosthodontic Resident Mock Exam was used, obtained from the American College of Prosthodontists. A total of 150 questions were initially considered, and resources were available for 106 questions. Both the base and fine-tuned models of ChatGPT-4 were tested under simulated exam conditions. Performance was assessed by comparing correct and incorrect responses. The Chi-square test was used to analyze accuracy, with significance set at p < 0.05. The Kappa coefficient was calculated to measure agreement between the models' responses.

resultsThe base model of ChatGPT-4 correctly answered 62.7% of the 150 questions. For the 106 questions with resources, the fine-tuned model answered 73.6% correctly. The Chi-square test showed a significant improvement in performance after fine-tuning (p < 0.001). The Kappa coefficient was 0.39, indicating moderate agreement between the models (p < 0.001). Performance varied by topic, with lower accuracy in areas such as Implant Prosthodontics, Removable Prosthodontics, and Occlusion, though the fine-tuned model consistently outperformed the base model.

conclusionsFine-tuning ChatGPT-4 with specific resources significantly enhances its accuracy in answering specialized prosthodontic exam questions. While the base model provides a solid baseline, fine-tuning is essential for improving AI performance in specialized fields. However, certain topics may require more targeted training to achieve higher accuracy.

Indexed as

Artificial IntelligenceEducational MeasurementProsthodonticsCross-Sectional StudiesGenerative Artificial IntelligenceHumansInternship and ResidencyUnited StatesArtificial intelligenceChatGPTDentalEducationNatural Language processingProsthodontics

Identifiers

PMID40410713
PMCPMC12102979

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.