Evidence map›Paper›PMID 40410701›Full record

ArticleBMC genomics2025

RNA-Seq uncovers endogenous NO-induced hormone signal transduction and carbon metabolism in response to PEG stress in alfalfa.

Ying Zhao, Xiaofang Zhang, Yizhen Wang, Qian Ruan, Baoqiang Wang, Xiaoyue Wen, Xiaohong Wei

Abstract read
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ying ZhaoCollege of Life Science and Technology, Gansu Agricultural University, Lanzhou, 730070, China.
Xiaofang ZhangCollege of Life Science and Technology, Gansu Agricultural University, Lanzhou, 730070, China.
Yizhen WangCollege of Life Science and Technology, Gansu Agricultural University, Lanzhou, 730070, China.
Qian RuanCollege of Life Science and Technology, Gansu Agricultural University, Lanzhou, 730070, China.
Baoqiang WangCollege of Life Science and Technology, Gansu Agricultural University, Lanzhou, 730070, China.
Xiaoyue WenCollege of Life Science and Technology, Gansu Agricultural University, Lanzhou, 730070, China.
Xiaohong WeiCollege of Life Science and Technology, Gansu Agricultural University, Lanzhou, 730070, China. weixh@gsau.edu.cn.

Funding

National Natural Science Foundation of China 32060401National Natural Science Foundation of China 32301775Scientific Research Start-up Funds for Openly-recruited Doctors of Gansu Agricultural University GAU-KYQD-2020-7
6 · The paper itself

Abstract

backgroundAlfalfa (Medicago sativa L.) has the benefits of high yield and nutritional value as a sustainable forage. However, the water deficit significantly limits its growth and yield performance. Nitric oxide (NO) is a signal molecule that can enhance plant tolerance. The majority of previous studies focus on the role of exogenous NO in plant tolerance. However, the underlying mechanism of endogenous NO in alfalfa drought tolerance remains largely unexplored.

resultsTo explore the mechanism of the endogenous NO-mediated water deficit resistance in the alfalfa, seedlings were exposed to polyethylene glycol 6000 (PEG) and NO scavenger (cPTIO). Results showed that PEG treatment significantly augmented alfalfa endogenous NO, MDA, O

conclusionsIn summary, our study innovatively proposes a mechanism model of how endogenous NO enhances alfalfa tolerance to water deficiency at the physiological and molecular levels. The novel candidate genes can give genetic resources for the subsequent molecular-assisted breeding of drought-resistant alfalfa crops.

Indexed as

CarbonMedicago sativaNitric OxidePlant Growth RegulatorsPolyethylene GlycolsSignal TransductionStress, PhysiologicalGene Expression Regulation, PlantRNA-SeqCarbonNitric OxidePlant Growth RegulatorsPolyethylene Glycol 6000Polyethylene GlycolsMedicago sativaNitric oxideTCA cycleTranscription regulationWater deficit

Identifiers

PMID40410701
PMCPMC12101008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.