Evidence map›Paper›PMID 40410692›Full record

ArticleBMC musculoskeletal disorders2025

Impact of traumatic intervertebral disc injury on loss of correction following pedicle screw fixation for thoracolumbar fractures.

Tongfei Ge, Wenbo Li, Jiayang Wu, Qingyuan Wang, Cong Li, Siming Wang, Wu Xiong, Jin Fan

Abstract read
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In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Tongfei Ge *Department of Orthopedics, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, China.
Wenbo Li *Department of Orthopedics, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, China.
Jiayang Wu *Department of Orthopedics, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, China.
Qingyuan WangDepartment of Orthopedics, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, China.
Cong LiDepartment of Orthopedics, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, China.
Siming WangDepartment of Orthopedics, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, China.
Wu XiongDepartment of Orthopedics, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, China.
Jin FanDepartment of Orthopedics, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, Jiangsu, China. fanjin@njmu.edu.cn.

Funding

Jiangsu Province Hospital High-level Talent Cultivation Program (Phase I) CZ0121002010039National Natural Science Foundation of China 82272499
6 · The paper itself

Abstract

backgroundTraumatic intervertebral disc injury, while frequently observed in thoracolumbar fractures, is often overlooked in clinical management. This research aimed to investigate how traumatic intervertebral disc injury influences spinal stability and to analyze the risk factors for correction loss after posterior pedicle screw fixation for thoracolumbar fractures.

methodsA retrospective analysis was performed on 194 thoracolumbar fracture patients who received pedicle screw fixation. The assessment of disc injury was conducted using magnetic resonance imaging (MRI). Patients were categorized into intervertebral disc injury (IDI) and non-IDI (nIDI) groups. The clinical variables included visual analog scale (VAS) score, and American Spinal Injury Association score. The radiological data, comprising the vertebral wedge angle (VWA), Cobb angle (CA), disc angle, disc height, anterior (AVBHr), midline (MVBHr), and posterior vertebral body height ratio (PVBHr), were compared before surgery, one week after the operation, and at final follow-up. The mean follow-up duration was 12.7 ± 7.0 months.

resultsThe mean VAS score showed significant improvement postoperatively. 22.6% of patients with IDI developed the intervertebral vacuum phenomenon. The IDI group exhibited significantly greater CA and VWA, as well as lower disc height, AVBHr and MVBHr than the non-IDI group at the last follow-up. Age (odds ratio [OR] = 1.038, 95% confidence interval [CI] = 1.011-1.066, P = 0.005), male (OR = 2.201, 95% CI = 1.107-4.377, P = 0.025), and IDI (OR = 2.463, 95% CI = 1.105-5.489, P = 0.028) were statistically significant risk factors for kyphosis correction loss according to multivariate logistic regression analysis.

conclusionTraumatic IDI contributes to loss of correction following thoracolumbar fractures and is closely associated with accelerated disc degeneration. Age, male, and IDI are independent risk factors for postoperative kyphosis recurrence in patients with thoracolumbar fractures.

Indexed as

Fracture Fixation, InternalIntervertebral DiscLumbar VertebraePedicle ScrewsSpinal FracturesThoracic VertebraeAdultAgedFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesRisk FactorsIntervertebral disc injuryIntervertebral vacuum phenomenonKyphosisPosterior pedicle screw fixationThoracolumbar fractures

Identifiers

PMID40410692
PMCPMC12100839

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.