ArticleBMC cardiovascular disorders2025
Extensive biatrial thrombus in transit across a patent foramen ovale: prompt diagnosis and management-a case report.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Biatrial Thrombus Crossing Foramen Ovale in a Patient with Atrial Fibrillation.Acta Cardiologica Sinica · 2026Article
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5 authors.
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Abstract
backgroundThrombus in transit (TIT), a rare and life-threatening condition, poses risks of pulmonary and paradoxical embolism which needs prompt diagnosis. Our case report highlights the significance of utilizing advanced imaging techniques for accurate and timely diagnosis of TIT and the potential life-saving role of surgical thrombectomy. This case report discusses a rare instance of biatrial thrombus associated with venous thromboembolism (VTE) and patent foramen ovale (PFO). A 66-year-old female with multiple comorbidities presented with dyspnea and fatigue. Imaging revealed large thrombi in both atria, extending via PFO. Concurrent acute deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) were identified. Emergency cardiac surgery successfully removed the thrombi, emphasizing the diagnostic and management challenges associated with biatrial thrombus and PFO.
conclusionPoint-of-care ultrasound (POCUS) plays a critical role in rapidly identifying TIT across a PFO. The time-sensitive and multidisciplinary medical management of TIT is crucial, requiring individualized strategies. CLINICAL TRIAL NUMBER: Not applicable. KEY CLINICAL MESSAGE: POCUS can be very helpful in providing a more appropriate image and more accurate diagnosis in patients with pulmonary embolism related to thrombus in transit (TIT) which is one of the most life-threatening medical conditions.
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