Evidence map›Paper›PMID 40410364›Full record

ArticleScientific reports2025

Screening of oral potentially malignant disorders and oral cancer using deep learning models.

Karishma Madhusudan Desai, Pragya Singh, Mahima Smriti, Vivek Talwar, Manav Chaudhary, George Paul, Subhas Chandra Kolli, Parisa Sai Raghava, Golla Vamshi Krishna, C V Jawahar and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Karishma Madhusudan DesaiTokyo Dental College, 2 Chome-9-18 Misakicho, Chiyoda City, Tokyo, 101-0061, Japan.
Pragya SinghINAI, International Institute of Information Technology, Hyderabad, 500032, India. chief.pragya009@gmail.com.ORCID http://orcid.org/0009-0003-2742-5690
Mahima SmritiINAI, International Institute of Information Technology, Hyderabad, 500032, India.
Vivek TalwarCVIT, International Institute of Information Technology, Hyderabad, 500032, India.
Manav ChaudharyINAI, International Institute of Information Technology, Hyderabad, 500032, India.
George PaulINAI, International Institute of Information Technology, Hyderabad, 500032, India.
Subhas Chandra KolliINAI, International Institute of Information Technology, Hyderabad, 500032, India.
Parisa Sai RaghavaINAI, International Institute of Information Technology, Hyderabad, 500032, India.
Golla Vamshi KrishnaINAI, International Institute of Information Technology, Hyderabad, 500032, India.
C V JawaharCVIT, International Institute of Information Technology, Hyderabad, 500032, India.
P K VinodiHUB-Data, International Institute of Information Technology, Hyderabad, 500032, India.ORCID http://orcid.org/0000-0003-2968-498X
Varma KonalaINAI, International Institute of Information Technology, Hyderabad, 500032, India.
Ramanathan SethuramanIntel Technology India Private Limited, Bengaluru, 560103, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer though preventable, shows high mortality and affect the overall quality of life when detected in late stages. Screening techniques that enable early diagnosis are the need of the hour. The present work aims to evaluate the effectiveness of AI screening tools in the diagnosis of OPMDs and Oral cancers via native or web-application (cloud) using smart phone devices. We trained and tested two deep learning models namely DenseNet201 and FixCaps using 518 images of the oral cavity. While DenseNet201 is a pre-trained model, we modified the FixCaps model from capsule network and trained it ground up. Standardized protocols were used to annotate and classify the lesions (suspicious vs. non-suspicious). In terms of model performance, DenseNet201 achieved an F1 score of 87.50% and AUC of 0.97; while FixCaps exhibited F1 score of 82.8% and AUC of 0.93. DenseNet201 model (20 M) serves as a robust screening model (accuracy 88.6%) that can be hosted on a web-application in the cloud servers; while the adapted FixCaps model with its low parameter size of 0.83 M exhibits comparable accuracy (83.8%) allowing easy transitioning into a native phone-based screening application.

Indexed as

Deep LearningEarly Detection of CancerMouth NeoplasmsFemaleHumansMass ScreeningDeep learningOral cancerOral potentially malignant disordersScreeningWeb application

Identifiers

PMID40410364
PMCPMC12102393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.