Evidence map›Paper›PMID 40410289›Full record

Trial reportScientific reports2025

Early mobilization in postoperative glioma patients real world impact on recovery and long term prognosis.

Xiaohang Chen, Lei Wan, Bei Wang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaohang ChenInstitute of Hepatobiliary Diseases of Wuhan University, Zhongnan Hospital of Wuhan University, Wuhan, 430071, Hubei, China.
Lei WanDepartment of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, Hubei, China. wanlei830@163.com.
Bei WangDepartment of Nursing, Zhongnan Hospital of Wuhan University, Wuhan, 430071, Hubei, China. 1745679052@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The implementation of early mobilization in postoperative care has been shown to expedite patient recovery. However, its widespread use among patients undergoing glioma resection is not firmly established. This study aimed to implement an early mobilization protocol in glioma patients and evaluate its effects on early recovery and long-term prognosis. Patients who underwent craniotomy for glioma treatment between January 2018 and December 2019 were enrolled in a randomized controlled trial comparing conventional perioperative care (control group) with conventional care plus a structured early mobilization protocol (experimental group). We collected data on early recovery and long-term prognosis from patients' electronic health records. Means and frequencies were evaluated using the Mann-Whitney U test, T-test, and chi-square test. The research team conducted standardized assessments in advance to ensure consistency. Postoperative primary outcomes revealed that the experimental group showed improvements of 39.06 points in activities of daily living and 0.86 points in numerical rating scale scores for pain, a 2.02 day shorter mean length of hospital stay (95% confidence interval [CI] 91.099-100.596, 0.403-1.691, 9.754-15.060, P < 0.001). Secondary outcomes also indicated that the experimental group had a 4.2 day shorter mean time to ambulation, a 3.48 day shorter mean duration of central venous catheter use, a 4.15 day shorter mean duration of gastric tube use, and a 3.64 day shorter mean duration of urethral catheter use. Furthermore, the experimental group demonstrated a significantly lower incidence of postoperative complications and reduced hospitalization expenses (P < 0.05). However, no statistically significant differences with secondary outcomes were observed in intraoperative blood loss or three-year prognosis between the two groups. Our findings show that an early mobilization protocol can promote early recovery in patients undergoing glioma resection without adversely affecting long-term prognosis. The protocol demonstrated both safety and cost-effectiveness, supporting its clinical implementation to improve postoperative functional recovery.

Indexed as

Brain NeoplasmsEarly AmbulationGliomaPostoperative CareActivities of Daily LivingAdultAgedCraniotomyFemaleHumansLength of StayMaleMiddle AgedPostoperative PeriodPrognosisRecovery of Function

Identifiers

PMID40410289
PMCPMC12102244

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.