Evidence map›Paper›PMID 40410258›Full record

ArticleScientific reports2025

The mediating role of depressive symptoms in the relationship between health literacy and suicide-related behaviors in middle school students.

Ronghuinan Zhang, Aini Liu, Yu Luo, Chang Peng, Hong Wang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ronghuinan ZhangCollege of Public Health, Chongqing Medical University, No. 61, University Town Middle Road, Huxi Street, Shapingba District, Chongqing, 401331, China.
Aini LiuCollege of Public Health, Chongqing Medical University, No. 61, University Town Middle Road, Huxi Street, Shapingba District, Chongqing, 401331, China.
Yu LuoCollege of Public Health, Chongqing Medical University, No. 61, University Town Middle Road, Huxi Street, Shapingba District, Chongqing, 401331, China.
Chang PengCollege of Public Health, Chongqing Medical University, No. 61, University Town Middle Road, Huxi Street, Shapingba District, Chongqing, 401331, China. pengchang333@cqmu.edu.cn.
Hong WangCollege of Public Health, Chongqing Medical University, No. 61, University Town Middle Road, Huxi Street, Shapingba District, Chongqing, 401331, China. 100113@cqmu.edu.cn.

Funding

National Natural Science Foundation of China 82404288the Postdoctoral Fellowship Program of CPSF GZC20242134
6 · The paper itself

Abstract

Suicide-related behaviors among adolescents have garnered increasing social attention, while few studies have revealed the association between health literacy and suicide-related behaviors, and the underlying mechanism. Thus, this study aims to explore the effect of health literacy on suicide-related behaviors in Chinese adolescents, as well as the potential mediating role of depressive symptoms. A cross-sectional, questionnaire-based study was conducted among 7182 students who were selected by using stratified cluster sampling in May 2023. The Adolescent Health Literacy Scale, Center for Epidemiologic Studies Depression Scale, and three questions about the suicide-related behaviors were used to collect data. Chi-square tests were performed to compare the differences in the distribution of suicide-related behaviors across health literacy levels as well as sociodemographic characteristics. Spearman correlation analysis was performed to assess the correlations between variables. Bootstrap methods were performed to test the mediating role of depressive symptoms. The results showed that the prevalence of suicidal ideation, planning, and attempts in the past 12 months among Chinese middle school students was 26.62%, 9.27%, and 4.55%, respectively. Inadequate health literacy levels exhibited significant and positive correlation with depressive symptoms, suicidal ideation, planning, and attempts. Additionally, depressive symptoms were correlated significantly and positively with three suicide-related behaviors. Mediation analysis showed that the relationship between health literacy and suicide attempts was fully mediated by depressive symptoms and the mediation proportion was 64.9%, while depressive symptoms partially mediated the relationship between health literacy and suicidal ideation and planning, with the mediation proportion was 78.4% and 70.0%, respectively. By shedding light on these mechanisms, comprehensive health literacy improvement programs may be promising in preventing depression and suicide-related behaviors among adolescents.

Indexed as

DepressionHealth LiteracyStudentsSuicideAdolescentChinaCross-Sectional StudiesFemaleHumansMaleSuicidal IdeationSuicide, AttemptedSurveys and QuestionnairesDepressionHealth literacyMediation analysisMiddle school studentsSuicide-related behaviors

Identifiers

PMID40410258
PMCPMC12102286

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.