ArticleScientific reports2025
Phytochemical, biological, DFT, and molecular docking evaluation of Euphorbia paralias.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Ethnopharmacological and Antiaging Evaluation of Salvia cadmica: Modulation of MMP1/MMP3 and Collagen in Oxidative Stress-Induced Senescence.Chemistry & biodiversity · 2026Article
- Natural chlocarbazomycins as potential adenosine A1 receptor antagonists: ligand-based and structure-based virtual screening, quantum chemical analysis and CNS MPO study.Molecular diversity · 2026Article
- Pharmacophore-based virtual screening, molecular docking, MD simulation, MM-GBSA energy calculation and DFT analysis for theRSC advances · 2026Article
- Computational validation and network pharmacology reveal the cardioprotective and hypolipidemic potential ofFrontiers in bioinformatics · 2026Article
- Article
- Efficacy of Nigella sativa L. and Trigonella foenum-graecum straw ethanolic extracts against some tomato pests in a greenhouse.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to bridge the knowledge gap in the unclear previous studies of the molecular processes that cause the biological activities of Euphorbia paralias by integrating phytochemical analysis with quantum chemical calculations and molecular docking investigations, providing unprecedented insights into the therapeutic potential of its chemical constituents. Seven important flavonoids were isolated and identified using spectroscopic techniques, and 34 and 13 additional compounds were identified via GC/MS analysis of the hexane and chloroform fractions, respectively. The crude methanol extract, some fractions, and isolated compounds were screened for antimicrobial activity against Gram-positive and Gram-negative bacteria. Among the tested constituents, β-sitosterol-3-O-β-D-glucoside 1, kaempferol-3-O-α-D-arabinopyranoside 4, and genistein-8-β-C-glucoside 6, as well as the chloroform and ethyl acetate fractions, demonstrated notable broad-spectrum antibacterial activity. The insecticidal activities of the butanol fraction and a combination of genistein-4'-O-β-D-glucopyranoside 2 and quercetin-3-O-β-D-glucoside 3 significantly inhibited Aphis gossypii and Amrasca biguttula, with LC
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.