ArticleBritish journal of anaesthesia2025
Impact of liberal preoperative clear fluid fasting regimens on the risk of pulmonary aspiration in children (EUROFAST): an international prospective cohort study.
Article in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07482345 (Impact of Three Different Preoperative Fasting Strategies on Gastric Ultrasound Findings and Anxiety Levels in Children Undergoing Inguinoscrotal Surgery), which is not on this map. Cited by 10 papers.
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The trial behind it
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Impact of Three Different Preoperative Fasting Strategies on Gastric Ultrasound Findings and Anxiety Levels in Children Undergoing Inguinoscrotal Surgery: A Prospective Randomized Trial
Who cites it
10 citing papers in PubMed.
- Article
- Preoperative fasting guidelines: A narrative review.European journal of anaesthesiology and intensive care · 2026Review
- When ideal positioning is impossible: can we limit pediatric gastric ultrasound to the supine semi-recumbent position?Translational pediatrics · 2026Article
- Safety of shorter fasting durations in paediatric surgery: a call for more robust evidence. Response to Br J Anaesth 2025: 135: 245-6.British journal of anaesthesia · 2025Article
- Preoperative fasting in paediatric anaesthesia: a movie with a predicable ending. Comment on Br J Anaesth 2025: 135: 14-6.British journal of anaesthesia · 2025Article
- Impact of liberal preoperative clear fluid fasting regimens on the risk of pulmonary aspiration in children (EUROFAST). Comment on Br J Anaesth 2025; 135: 141-7.British journal of anaesthesia · 2025Article
- Preoperative fasting in paediatric anaesthesia: a movie with a predicable ending.British journal of anaesthesia · 2025Article
- Beyond "Fast From Midnight"-The New Fasting Norm Is Here.ANZ journal of surgeryArticle
- Optimizing Nutrition in Pediatric Burn Patients: A Quality Improvement Initiative.Pediatric quality & safetyArticle
- Modernizing perioperative fasting: Liberal clear liquids, glucagon-like peptide-1 receptor agonists, and point-of-care gastric ultrasound.Saudi journal of anaesthesiaReview
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreoperative fasting regimens designed to minimise the risk of pulmonary aspiration have undergone significant changes, but unequivocal evidence of the safety of reducing clear fluid fasting has been lacking. We compared the risk of pulmonary aspiration in children using three different recommendations for clear fluid fasting.
methodsIn this prospective multicentre cohort study, centres with >1000 paediatric anaesthesia cases per year were eligible. Regurgitation events, whether they were transient or led to consequences affecting postoperative care, were reported in detail. All centres also reported the number of anaesthetised children per year and which preoperative fasting regimen they used.
resultsThe 31 participating centres contributed a total of 306 900 anaesthetic procedures. The incidence of confirmed pulmonary aspiration was 1.18:10 000 in the sip-til-send group, 0.96:10 000 in the ≥1 h group, and 1.83:10 000 in the control group. There was no mortality as a result of aspiration. The 95% confidence intervals of the differences in confirmed pulmonary aspiration between the control group and the ≥1 h clear fluid fasting and the sip-til-send group were -0.344 to 3.76 and -1.48 to 3.63, respectively. Both sip-til-send and ≥1 h clear fluid fasting were statistically noninferior to ≥2 h clear fluid fasting regarding the incidence of confirmed aspiration, transient regurgitation, and regurgitation leading to escalation of care or intensive care.
conclusionsThe study provides evidence for the safety of reducing preoperative fasting time for clear fluids in children aged <16 yr from 2 h to ≤1 h.
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