Evidence map›Paper›PMID 40409961›Full record

ArticleBMJ open2025

Prevalence and burden of asthma in five European countries: a retrospective cross-sectional study.

Asif H Khan, Imène Gouia, Juby Jacob-Nara, Siddhesh Kamat, Dena Jaffe, deMauri Mackie, Bridget L Balkaran, Juan Wisnivesky

Abstract read
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Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asif H KhanSanofi, Morristown, New Jersey, USA asif.khan@sanofi.com.
Imène GouiaSanofi, Chilly-Mazarin, France.
Juby Jacob-NaraSanofi, Morristown, New Jersey, USA.
Siddhesh KamatRegeneron Pharmaceuticals Inc, Tarrytown, New York, USA.
Dena JaffeOracle Life Sciences, North Kansas City, Missouri, USA.
deMauri MackieOracle Life Sciences, North Kansas City, Missouri, USA.
Bridget L BalkaranOracle Life Sciences, North Kansas City, Missouri, USA.
Juan WisniveskyDivision of General Internal Medicine and Pulmonary and Critical Care Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the burden of asthma in five European countries (5EU; France, Germany, Italy, Spain and United Kingdom [UK]).

designA retrospective cross-sectional study was conducted based on the data from the 2018 National Health and Wellness Survey. Health-related quality of life (HRQoL), work productivity and activity impairment, and healthcare resource utilisation (HCRU) were compared between different groups: asthma versus non-asthma, mild/moderate/severe asthma versus non-asthma and moderate/severe asthma versus mild asthma. SETTINGS: Internet-based survey across Western Europe.

participantsAdult patients (aged ≥18 years) with self-reported physician diagnosis of asthma and experienced asthma symptoms in the past 12 months. OUTCOME MEASURES: Socio-demographic characteristics, asthma-related outcomes, HRQoL and productivity, HCRU and prevalence of asthma.

resultsThe prevalence of asthma in the 5EU was 6.7% (95% CI: 6.5% to 6.9%), with the UK reporting the highest rates (10.4%; 95% CI: 9.9% to 10.9%). About 52.0% of the respondents had mild asthma, 27.9% had moderate and 20.1% had severe asthma. The asthma group reported significantly poorer HRQoL, higher rates of overall work productivity impairment and activity impairment, and a greater number of visits to emergency room, healthcare provider and hospitalisations versus the non-asthma group (all p<0.001). Similar trend was observed for all outcomes among respondents with moderate or severe versus mild asthma.

conclusionAsthma prevalence and burden are still high in Western Europe, indicating the need for effective interventions that could lead to improved outcomes.

Indexed as

AsthmaSurveys and QuestionnairesActivities of Daily LivingAdultAgedCost of IllnessCross-Sectional StudiesEfficiencyEuropeFemaleFranceGermanyHealth ResourcesHumansInternetItalyAsthmaEPIDEMIOLOGYHospitalizationPatient Reported Outcome MeasuresQuality of Life

Identifiers

PMID40409961
PMCPMC12104913

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.