ArticleJACC. Case reports2025
Cardiogenic Shock as the Initial Manifestation of Thyrotoxicosis.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
backgroundThyroid storm is a condition characterized by excess circulating thyroid hormones with the development of severe clinical manifestations that may progress to cardiogenic shock, multiorgan failure, and death. CASE SUMMARY: A 41-year-old woman with Graves' disease and poor medical compliance presented to the emergency department with thyroid storm. After initiation of antithyroid and beta-blocker treatment, the patient developed cardiogenic shock and multiorgan failure, requiring placement of a temporary mechanical circulatory support device, immunosuppressive treatment with corticosteroids, and plasmapheresis. She had a good clinical response and underwent total thyroidectomy. DISCUSSION: Thyroid storm is a rare cause of cardiogenic shock and multiorgan failure with a high mortality rate despite medical treatment. The case emphasizes the usefulness of multidisciplinary management to avoid adverse outcomes. TAKE-HOME MESSAGE: The case demonstrates the usefulness of alternative therapies (eg, plasmapheresis) and caution in the use of beta-blockers in patients with thyroid storm.
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