Evidence map›Paper›PMID 40409848›Full record

ArticleJACC. Case reports2025

Isolated Posterior Mitral Valve Cleft Diagnosed by 3D Echocardiography in an Elderly Woman.

Adam M Khalil, Nadya Almatrooshi, Umer Darr, Aiman Smer, Mohammed E Khalil

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adam M KhalilWeill Cornell Medicine, Education City, Qatar.
Nadya AlmatrooshiCleveland Clinic, Abu Dhabi, United Arab Emirates.
Umer DarrCleveland Clinic, Abu Dhabi, United Arab Emirates.
Aiman SmerCleveland Clinic, Abu Dhabi, United Arab Emirates.
Mohammed E KhalilCleveland Clinic, Abu Dhabi, United Arab Emirates. Electronic address: KhalilM3@clevelandclinicabudhabi.ae.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIsolated posterior mitral valve cleft (MVC) is a rare congenital anomaly that can be easily overlooked with standard 2-dimensional imaging. CASE SUMMARY: A 94-year-old woman with progressive heart failure symptoms was found to have severe mitral regurgitation due to an isolated posterior MVC. Three-dimensional echocardiography provided detailed visualization of the lesion's anatomy and confirmed the diagnosis. After excluding a percutaneous repair due to the cleft's complexity, she underwent minimally invasive surgical repair, resulting in substantial symptomatic improvement. DISCUSSION: Posterior MVCs are infrequently reported and often missed by conventional imaging. Advances in 3-dimensional echocardiography have enhanced diagnostic accuracy, guiding targeted interventions. This case shows the importance of comprehensive imaging for such rare anomalies and the feasibility of surgical repair, even in elderly patients.

Indexed as

3-dimensional echocardiographyheart failure in elderlyposterior mitral valve cleft

Identifiers

PMID40409848
PMCPMC12243044

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.