Evidence map›Paper›PMID 40409736›Full record

ArticleThe Journal of steroid biochemistry and molecular biology2025

Changes in vitamin D biomarkers across pregnancy and by maternal BMI: A secondary analysis of data and biospecimens from the National Children's Study.

Skylar Mercer, Xianyan Chen, Biplav B Tiwari, Alex Anderson, Sheree L Boulet, Janani Rajbhandari, Sina Gallo

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In one paragraph

Article in The Journal of steroid biochemistry and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Skylar MercerDepartment of Nutritional Sciences, University of Georgia, Dawson Hall, 305 Sanford Dive, Athens, GA 30602, United States.
Xianyan ChenEpidemiology & Biostatistics, University of Georgia, B.S. Miller Hall, Health Sciences Campus, 101 Buck Road, Athens, GA 30602, United States.
Biplav B TiwariDepartment of Health Policy and Management, University of Georgia, Wright Hall, Health Sciences Campus, 100 Foster Road, Athens, GA 30602, United States.
Alex AndersonDepartment of Nutritional Sciences, University of Georgia, Dawson Hall, 305 Sanford Dive, Athens, GA 30602, United States.
Sheree L BouletDepartment of Obstetrics and Gynecology, Boston University Chobanian & Avedisian School of Medicine, Boston Medical Center, Boston, MA 02118, United States.
Janani RajbhandariEpidemiology & Biostatistics, University of Georgia, B.S. Miller Hall, Health Sciences Campus, 101 Buck Road, Athens, GA 30602, United States; Department of Health Policy and Management, University of Georgia, Wright Hall, Health Sciences Campus, 100 Foster Road, Athens, GA 30602, United States.
Sina GalloDepartment of Nutritional Sciences, University of Georgia, Dawson Hall, 305 Sanford Dive, Athens, GA 30602, United States. Electronic address: sina.gallo@uga.edu.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
NCATS NIH HHS UL1 TR002378
6 · The paper itself

Abstract

Obesity during pregnancy is associated with increased risk for vitamin D deficiency in both the mother and offspring. Free or unbound 25-hydroxyvitamin D (25(OH)D) is the biologically active form as compared to total 25(OH)D, which may be important in the assessment of vitamin D status during conditions like pregnancy where vitamin D binding protein (VDBP) is affected. Little is known about how pre-pregnancy BMI affects changes in vitamin D markers during pregnancy. This is a secondary analysis of data and biospecimens from the 2009-2014 National Children's Study (NCS). The current analysis included 50 participants (50 % normal weight [18.5 ≥BMI<25 kg/m

Indexed as

Body Mass IndexPregnancy ComplicationsVitamin DVitamin D DeficiencyAdultBiomarkersFemaleHumansInfant, NewbornObesityPregnancyUnited StatesVitamin D-Binding Protein25-hydroxyvitamin DBiomarkersVitamin DVitamin D-Binding ProteinBody mass indexFree vitamin DLiquid chromatography-tandem mass spectrometryMaternal obesityPregnancyVitamin DVitamin D binding protein

Identifiers

PMID40409736
PMCPMC12158623

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.