Evidence map›Paper›PMID 40408398›Full record

ArticlePloS one2025

Development and validation of a questionnaire assessing pharmacists' knowledge and practice towards antimicrobial stewardship in oncology care.

Ali Haider Mohammed, Bassam Abdul Rasool Hassan, Lim Jie Sern, Lim Jing Xuan, Leong Jia Yun, Lim Jing En, Dinesh Sangarran Ramachandram, Angelina Lim, Juman Abdulelah Dujaili, Ali Qais Blebil

Abstract readValidation Study
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ali Haider MohammedSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
Bassam Abdul Rasool HassanDepartment of Pharmacy, Al Rafidain University College, Baghdad, Iraq.ORCID https://orcid.org/0000-0001-5822-0442
Lim Jie SernSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
Lim Jing XuanSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
Leong Jia YunSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
Lim Jing EnSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
Dinesh Sangarran RamachandramSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
Angelina LimFaculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Juman Abdulelah DujailiSwansea University Medical School, Swansea University, Swansea, United Kingdom.
Ali Qais BlebilSwansea University Medical School, Swansea University, Swansea, United Kingdom.ORCID https://orcid.org/0000-0002-7480-1260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer patients who receive immunosuppressive therapy are vulnerable to infections due to their compromised immune systems. Therefore, research in promoting the prudent use of antibiotics in this population is essential to optimise patient outcomes and reduce resistance development. The purpose of this study is to develop and validate the Knowledge and Practice of Antimicrobial Stewardship in the Oncology Care Questionnaire (KP-AMS-OC-Q).

methodThis research is performed in 2 phases. Phase I includes the questionnaire development, item generation, content validity and pilot testing. Phase II encompasses the dissemination of questionnaires to hospital pharmacists and the psychometric evaluation of the validation and reliability of KP-AMS-OC-Q. Specifically, IRT is used to evaluate the knowledge domains, EFA for the practice domains, and Cronbach alpha to measure reliability.

resultThe finalised version of the questionnaire consisted of 112 items, including 7 social demographics, 49 knowledge, and 56 practice items. IRT conducted has revealed an acceptable difficulty parameter (-3 to +3) in the knowledge domain. Furthermore, EFA has shown a strong internal association between the items and factors, with each item reaching the minimum acceptable factor loading value (>0.3). Besides this, the internal consistency of this questionnaire is favourable, indicated by the Cronbach alpha coefficient of 0.899.

conclusionThe results of this study have validated that KP-AMS-OC-Q possesses exceptional psychometric qualities, making it appropriate to measure pharmacists' knowledge and practice towards antimicrobial stewardship (AMS) in oncology care.

Indexed as

Antimicrobial StewardshipHealth Knowledge, Attitudes, PracticeNeoplasmsPharmacistsAdultFemaleHumansMaleMedical OncologyMiddle AgedPsychometricsReproducibility of ResultsSurveys and Questionnaires

Identifiers

PMID40408398
PMCPMC12101630

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.