Evidence map›Paper›PMID 40408118›Full record

ArticleTranslational vision science & technology2025

Usefulness of Measuring Corneal Stiffness in Predicting the Reduction of Intraocular Pressure With Microhook Ab Interno Trabeculotomy.

Kei Asaoka, Yuri Fujino, Honami Fukuyo, Hiroshi Murata, Shuichiro Aoki, Kaori Ishii, Yoshiaki Kiuchi, Ryo Asaoka

Abstract read
In one paragraph

Article in Translational vision science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kei AsaokaDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan.
Yuri FujinoDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan.
Honami FukuyoDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan.
Hiroshi MurataDepartment of Ophthalmology, National Center for Global Health and Medicine, Tokyo, Japan.
Shuichiro AokiDepartment of Ophthalmology, Sapporo City General Hospital, Sapporo, Japan.
Kaori IshiiDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan.
Yoshiaki KiuchiDepartment of Ophthalmology and Visual Science, Hiroshima University, Hiroshima, Japan.
Ryo AsaokaDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the predictive factors for intraocular pressure (IOP) after microhook ab interno trabeculotomy (TLO). Methods: We included 147 eyes of 97 glaucoma patients who underwent TLO. We recorded the following preoperative parameters: systemic parameters (age, height, body mass index, systolic blood pressure, diastolic blood pressure, and history of smoking), blood examination scores, ocular parameters (preoperative Goldmann applanation tonometry [GAT]-IOP, central corneal thickness, type of glaucoma, and preoperative use of anti-glaucoma eyedrops), and Ocular Response Analyzer (ORA) parameters (corneal resistance factor [CRF], corneal hysteresis, corneal-compensated intraocular pressure). We analyzed the preoperative parameters associated with postoperative GAT-IOP. Subsequently, similar analysis was performed using a corneal visualization Scheimpflug technology instrument (Corvis ST) parameters, instead of the ORA parameters. Postoperative GAT-IOP was measured after 12 months from TLO. Results: When ORA parameters were used, preoperative high hemoglobin (Hb), high C-reactive protein (CRP), use of brimonidine tartrate, and high CRF were significant risk factors for postoperative high GAT-IOP, in addition to type of glaucoma. When Corvis ST parameters were used, preoperative high serum Hb, high serum CRP, usage of brimonidine tartrate, high biomechanical intraocular pressure, high stress-strain index, and low time to maximal displacement of whole eye movement were significant risk factors for postoperative high GAT-IOP. Conclusions: ORA and Corvis ST measurements suggested that stiff cornea was a risk factor for high postoperative GAT-IOP after TLO, in addition to preoperative high Hb, high CRP, and the use of brimonidine tartrate. Translational Relevance: Stiff cornea is a risk factor for high postoperative intraocular pressure after trabeculotomy.

Indexed as

CorneaGlaucomaIntraocular PressureTrabeculectomyAdultAgedFemaleHumansMaleMiddle AgedTonometry, Ocular

Identifiers

PMID40408118
PMCPMC12118510

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.