Evidence map›Paper›PMID 40407964›Full record

ReviewCurrent allergy and asthma reports2025

Hypereosinophilia in Children.

Tyesha Coleman, Richard Bickel, John Noel, Kathleen R May

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tyesha ColemanDepartment of Pediatrics, Division of Allergy-Immunology and Pediatric Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, USA.
Richard BickelDepartment of Pediatrics, Division of Allergy-Immunology and Pediatric Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, USA.
John NoelDepartment of Pediatrics, Division of Allergy-Immunology and Pediatric Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, USA.
Kathleen R MayDepartment of Pediatrics, Division of Allergy-Immunology and Pediatric Rheumatology, Medical College of Georgia at Augusta University, Augusta, GA, USA. kamay@augusta.edu.ORCID https://orcid.org/0000-0002-3761-1900

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewHypereosinophilia is defined as an absolute eosinophil count greater than 1500 cells/mm3. This is a condition often observed in the pediatric population, with benign/self-resolving to life-threatening etiologies. Identifying the cause of hypereosinophilia can be challenging, given its broad associated differential diagnosis and diversity of presentations. This review provides an overview of eosinophil biology and explores causes of hypereosinophilia in children, emphasizing diagnostic and therapeutic challenges, while underscoring the importance of recognizing rare causes including primary hypereosinophilic syndrome (HES). RECENT

findingsClassification of hypereosinophilic subtypes has evolved, as has understanding of etiologies with advances in modern diagnostic tools. Newer therapeutic options with low side-effect profiles have expanded treatment options in patients with HES. Despite recent improvements in medical management, HES remains a serious medical condition with considerable morbidity and potential mortality. Early identification and appropriate treatment can improve prognosis and reduce the burden of disease in children.

Indexed as

EosinophiliaEosinophilsHypereosinophilic SyndromeChildDiagnosis, DifferentialHumansPrognosisEosinophilsHESHypereosinophiliaHypereosinophilic syndromePediatrics

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.