Evidence map›Paper›PMID 40407929›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2025

Long-term outcomes after elective inguinal hernia mesh-repair in patients with inflammatory bowel disease.

Hans Lovén, Rune Erichsen, Anders Tøttrup, Thue Bisgaard

Abstract read
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hans LovénCentre for Surgical Science, Zealand University Hospital, University of Copenhagen, Lykkebækvej 1, Køge, 4600, Denmark. hans.loven@gmail.com.ORCID 0000-0002-7887-3579
Rune ErichsenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Anders TøttrupDepartment of Surgery, Region Hospital Viborg, Viborg, Denmark.
Thue BisgaardDepartment of Surgery, North Denmark Regional Hospital, Hjørring, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnowledge of long-term outcomes following elective inguinal hernia mesh-repair in patients with inflammatory bowel disease (IBD) remains limited. Pathophysiological differences between Crohn's disease (CD) and ulcerative colitis (UC) may influence mesh-related complications and recurrence risk. The primary objective was to assess the reoperation risk for mesh-related complications, and secondarily, recurrence after inguinal hernia mesh-repair in patients with CD and UC. The impact of fistulising disease (intra-abdominal/perianal) and surgical technique (open/laparoscopic) on both outcomes was also analysed based on the available data.

methodsThis nationwide cohort study (2007-2016) followed IBD patients undergoing elective inguinal hernia mesh-repair to assess risks of reoperation for mesh-related complications or recurrence. Risks were estimated using cumulative incidence and Cox regression analyses.

resultsAmong 1,072 patients with IBD (CD = 264, UC = 698, IBD-unclassified = 110), the five-year reoperation risk was 0.5% for mesh-related complications and 5.7% for recurrence. Fistulising disease was present in 6.9% (n = 74) of all patients with IBD: perianal in 95% (n = 70) and intra-abdominal in 5% (n = 4). There were too few mesh-related complications (n = 5) to support statistical analysis of this outcome. Recurrence risk was not significantly affected by IBD subtype: CD (reference), UC (HR = 1.67, 95% CI: 0.77-3.64), IBD-U (HR = 0.91, 95% CI: 0.24-3.44), or surgical technique: transabdominal preperitoneal (TAPP) (reference), and Lichtenstein (HR = 0.80, 95% CI: 0.43-1.47).

conclusionThis study suggests that inguinal hernia mesh-repair is also safe among IBD patients regardless of subtype, surgical technique, or perianal fistulation. Similarly, recurrence risk was unaffected by these factors. Limited data prevented conclusions on intra-abdominal fistulising disease as a potential risk-factor for poor surgical outcomes.

Indexed as

Colitis, UlcerativeCrohn DiseaseHernia, InguinalHerniorrhaphyInflammatory Bowel DiseasesPostoperative ComplicationsSurgical MeshAdultAgedElective Surgical ProceduresFemaleHumansMaleMiddle AgedRecurrenceReoperationCrohn’s diseaseFistulising diseaseIBDInguinal hernia repairLichtensteinMeshrelated complicationsRecurrenceTAPPUlcerative colitis

Identifiers

PMID40407929
PMCPMC12102129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.