SynthesisArchives of gynecology and obstetrics2025
Management of pregnant women with endocervical and decidual polyps: a systematic review and meta-analysis.
Synthesis in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Pregnancy outcomes and risk factors of decidual polyps in the first trimester after fresh cycle embryo transfer.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Targeted Cauterization of Bleeding Cervical Polyps During Pregnancy: A Case Series.Clinical case reports · 2026Article
- Clinical application of hysteroscopic decidual polypectomy in pregnant women.BMC pregnancy and childbirth · 2026Article
- Vaginoscopic polypectomy for cervical polyps during pregnancy: an analysis of safety and influencing factors for pregnancy outcomes.Frontiers in medicine · 2026Article
- Vitamin D, immune microenvironment, and cervical lesions: mechanisms and therapeutic strategies from polyps to carcinoma.Frontiers in nutrition · 2025Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe impact of polypectomy of endocervical and decidual polyps during pregnancy on the risk of spontaneous late miscarriage and preterm delivery has not been determined. The existing systematic reviews included only three studies that could not yield definite conclusions.
methodsThe PubMed, EMBASE, Cochrane Library, Wanfang Med and CNKI databases were searched from inception until July 1, 2024. Studies of women who were diagnosed with endocervical and decidual polyps during pregnancy and who received treatment or observation were included. Studies without a control group were excluded. Randomized controlled trials and case‒control, cohort, and cross-sectional studies were included in this review. Two reviewers independently screened the studies for inclusion and extracted the data. Methodological quality was evaluated with the Newcastle‒Ottawa Scale. Statistical analysis was performed via Review Manager software version 5.4, employing fixed-effects or random-effects meta-analyses as appropriate, to estimate odds ratios with 95% confidence intervals.
resultsOf the 1696 initially identified articles, 12 met the inclusion criteria and were included in the review. These 12 studies, comprising data from 8337 women, underwent quantitative analysis. The results of the meta-analyses revealed a significantly greater risk of miscarriage (OR, 11.19; CI 4.63-27.04) and preterm delivery (OR, 9.41; CI 3.40-26.04) in women with endocervical polyps than in those without. Endocervical polypectomy had no significant influence on subsequent miscarriage (OR, 1.28; CI 0.69-2.36) or preterm delivery (OR, 1.12; CI 0.36-3.49). Conversely, the removal of decidual polyps was associated with a significantly greater risk of miscarriage (OR, 2.77; CI 1.45-5.27) and preterm birth (OR, 3.42; CI 1.09-10.72) than endocervical polypectomy was. Furthermore, polypectomy performed before the 12th gestational week was associated with an increased risk of miscarriage (OR, 2.87; CI 1.08-7.59), although not preterm delivery (OR, 1.18; CI 0.61-2.30).
conclusionsIn pregnant women, polypectomy for endocervical or decidual polyps does not have a significant negative effect on miscarriage or preterm delivery, and it is better to perform the operation after the 12th gestational week. However, the presence of decidual polyps may pose a heightened risk for adverse obstetric outcomes.
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