Evidence map›Paper›PMID 40407867›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

Resveratrol, a calorie restriction mimetic, protects AlCl

Vijay S Benade, Pradeep Jayarajan, Nandakumar Krishnadas, Ramakrishna Nirogi

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vijay S BenadeSuven Life Sciences, Serene Chambers, Road # 7, Banjara Hills, Hyderabad, 500 034, India.
Pradeep JayarajanSuven Life Sciences, Serene Chambers, Road # 7, Banjara Hills, Hyderabad, 500 034, India.
Nandakumar KrishnadasDepartment of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE), Manipal, India.
Ramakrishna NirogiSuven Life Sciences, Serene Chambers, Road # 7, Banjara Hills, Hyderabad, 500 034, India. nvsrk@suven.com.ORCID http://orcid.org/0000-0002-2045-0784

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodegenerative diseases, such as Alzheimer's diseases (AD), are becoming more prevalent as population ages. Recent researches indicate possible involvement of increased oxidative stress and free radicals in AD-related changes, suggesting that therapeutic efforts aimed at the removal of reactive oxygen species (ROS) or prevention of their formation may be beneficial in AD. Resveratrol, a polyphenol found in red wines, demonstrated antioxidant and anti-aging effects in various in vitro and in vivo studies. In the current work, resveratrol was evaluated in animal model of cognitive impairment and/or neurodegeneration as a potential treatment approach for AD. Rats were treated with aluminum chloride (AlCl

Indexed as

Aluminum CompoundsAntioxidantsChloridesCognition DisordersCognitive DysfunctionNeuroprotective AgentsNeurotoxicity SyndromesOxidative StressStilbenesAluminum ChlorideAnimalsCaloric RestrictionCognitionDisease Models, AnimalMaleMaze LearningAluminum ChlorideAluminum CompoundsAntioxidantsChloridesNeuroprotective AgentsResveratrolSirt1 protein, ratSirtuin 1StilbenesAgingAlzheimer’s diseaseCalorie restrictionOxidative stressResveratrolSirtuins

Identifiers

PMID40407867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.