Evidence map›Paper›PMID 40407835›Full record

Trial reportLasers in medical science2025

Clinical and radiographic evaluation of Er: YAG laser-assisted direct pulp capping in permanent teeth with carious exposure.

Neha Jasrasaria, Rakesh Kumar Yadav, Rini Tiwari

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Neha JasrasariaKing George's Medical University, Lucknow, India.
Rakesh Kumar YadavKing George's Medical University, Lucknow, India. rakeshanita10@yahoo.in.
Rini TiwariKing George's Medical University, Lucknow, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe study aimed to evaluate the clinical and radiographic outcomes of three treatment modalities: Biodentine alone, Er: YAG laser followed by Biodentine, and Er: YAG laser alone. The primary objective was to determine whether the use of Er: YAG laser enhances the success rate of direct pulp capping (DPC) in cariously exposed permanent teeth.

methodsThis study included 42 participants with mature permanent teeth requiring DPC, randomly assigned to three groups of 14 patients each. Group 1 received Biodentine alone, Group 2 underwent Er: YAG laser irradiation followed by Biodentine application, and Group 3 was treated with Er: YAG laser. The laser parameters used for enamel cutting and cavity preparation were: output power 8.0 W, energy 400 mJ, fluence 10 J/cm², spot size 0.8 mm, frequency 20 Hz, air 80%, and water 60%, in contact mode. For carious dentin removal, parameters were adjusted to 4.0 W power, 200 mJ energy, fluence 3 J/cm², frequency 20 Hz, air 90%, and water 30%, maintaining the same spot size. Pulp irradiation was performed using a 0.6 mm spot size, 0.5 W output power, 30 mJ energy and frequency 15 Hz in non-contact mode with no water spray, at a distance of 1.5 mm from the pulp. Laser was applied in a sweeping motion for 15 s per application, repeated 5-20 times until hemostasis was achieved. Clinical and radiographic evaluations were conducted at baseline, 3 months, 6 months and 12 months. Success was defined as the absence of pain, sensitivity, or pathology and evidence of dentin bridge formation on radiographs. Statistical analysis was performed to compare outcomes across groups.

resultsAll three groups demonstrated favourable clinical and radiographic success rates. Group 2 (Er: YAG laser + Biodentine) showed a statistically significant higher success rate compared to the other groups, particularly in terms of dentin bridge formation (p = 0.01) and reduced postoperative sensitivity (p = 0.03). Group 1 and Group 3 also performed well, but the outcomes in Group 3 were slightly inferior due to limited dentin bridge formation (p = 0.04).

conclusionThe inclusion of Er: YAG laser in DPC procedures enhances treatment outcomes, particularly when combined with Biodentine. This approach offers a promising alternative for vital pulp therapy in mature permanent teeth, ensuring better dentin bridge formation and clinical success. CLINICAL

trial registrationClinical trial registration details (Registry-Clinical Trials Registry - India, Trial registration number-CTRI/2022/04/041678, and date of registration-06/04/2022).

Indexed as

Dental CariesDental Pulp CappingLasers, Solid-StateAdolescentAdultCalcium CompoundsDentition, PermanentFemaleHumansMaleMiddle AgedPulp Capping and Pulpectomy AgentsSilicatesTreatment OutcomeYoung AdultCalcium CompoundsPulp Capping and Pulpectomy AgentsSilicatestricalcium silicateBiodentineErbium-doped yttrium aluminum garnet lasersPulp exposureSolid state lasersTertiary dentinVital pulp therapy

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.