Evidence map›Paper›PMID 40407751›Full record

ArticleACS infectious diseases2025

Design of Epitopes from

Letícia Alves Borghezan, Lara Cândida de Sousa Machado, Iara Barreto Neves Oliveira, Mírian Ívens Fagundes, Nicoly Silveira Apolidório, Renato Canevari Dutra da Silva, Victor Garcia Freire, Antonio Augusto Schafer, Rahisa Scussel, Ricardo Andrez Machado-de-Ávila

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Letícia Alves BorghezanPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Universitário, 88806-000 Criciúma, Santa Catarina, Brazil.
Lara Cândida de Sousa MachadoPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Universitário, 88806-000 Criciúma, Santa Catarina, Brazil.
Iara Barreto Neves OliveiraFaculdade de Medicina, Universidade de Rio Verde, Avenida T-13 Qd. S-06, Lts.08/13. Setor Bela Vista, 74823-440 Goiânia, Goiás, Brazil.
Mírian Ívens FagundesPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Universitário, 88806-000 Criciúma, Santa Catarina, Brazil.ORCID 0000-0001-7451-2285
Nicoly Silveira ApolidórioPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Universitário, 88806-000 Criciúma, Santa Catarina, Brazil.
Renato Canevari Dutra da SilvaFaculdade de Medicina, Universidade de Rio Verde, Fazenda Fontes do Saber, Campus Universitário, 75901-970 Rio Verde, Goiás, Brazil.
Victor Garcia FreirePrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Universitário, 88806-000 Criciúma, Santa Catarina, Brazil.
Antonio Augusto SchaferFaculdade de Medicina, Universidade de Rio Verde, Fazenda Fontes do Saber, Campus Universitário, 75901-970 Rio Verde, Goiás, Brazil.
Rahisa ScusselPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Universitário, 88806-000 Criciúma, Santa Catarina, Brazil.ORCID 0000-0002-0931-604X
Ricardo Andrez Machado-de-ÁvilaPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Universitário, 88806-000 Criciúma, Santa Catarina, Brazil.ORCID 0000-0002-1303-0490

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Syphilis, a multistage sexually transmitted infection, causes severe complications if untreated. Accurate diagnosis remains difficult due to the low protein content of

Indexed as

Antigens, BacterialEpitopesLipoproteinsSyphilisTreponema pallidumAdultAntibodies, BacterialCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHumansMalePeptidesPrognosisSensitivity and SpecificitySyphilis SerodiagnosisAntibodies, BacterialAntigens, BacterialEpitopesLipoproteinsPeptidesepitopesynthetic peptidestreponemal lipoproteins

Identifiers

PMID40407751
PMCPMC12172048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.