Evidence map›Paper›PMID 40407688›Full record

SynthesisEpileptic disorders : international epilepsy journal with videotape2025

Lateralizing value of ictal head turning: A systematic review and meta-analysis.

Melita Cacic Hribljan, Georg Zimmermann, Sándor Beniczky

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Epileptic disorders : international epilepsy journal with videotape, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Lateralizing value of ictal head turning: A systematic review and meta-analysis.Epileptic disorders : international epilepsy journal with videotape · 2025
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Melita Cacic HribljanDepartment of Clinical Neurophysiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Georg ZimmermannDepartment of Neurology, Neurological Intensive Care and Neurorehabilitation, Christian Doppler University Hospital, Paracelsus Medical University and Center for Cognitive Neuroscience, Member of the European Reference Network EpiCARE, Salzburg, Austria.ORCID https://orcid.org/0000-0002-8282-1034
Sándor BeniczkyDepartment of Clinical Neurophysiology, Danish Epilepsy Center, Dianalund, Denmark.ORCID https://orcid.org/0000-0002-6035-6581

Funding

Excellence in Digital Sciences and Interdisciplinary Technologies 20204-WISS/263/6-6022WISS 2025 Projects 'IDA-Lab Salzburg' 20102-F1901166-KZPWISS 2025 Projects 'IDA-Lab Salzburg' 20204-WISS/225/197-2019
6 · The paper itself

Abstract

objectiveTo elucidate the lateralizing value of ictal head turning in focal epilepsy and provide guidance for interpreting ictal semiology within the framework of presurgical evaluation.

methodsWe conducted a systematic review of ictal head turning. We included studies reporting ictal head turning (versive, nonversive, and gyration) captured in video-EEG recordings during presurgical evaluation. We assessed potential selection and assessment bias and evaluated confidence in the epileptogenic zone based on reported comparators-including resection site and surgical outcomes, intracerebral EEG, and MRI findings. Studies were classified as high quality if potential bias was low and confidence in the epileptogenic zone was high.

resultsVersive head turning is usually contralateral to the epileptogenic zone (high level of evidence). Nonversive head turning is most often ipsilateral to the epileptogenic zone in temporal lobe epilepsy (high level of evidence) and contralateral in occipital lobe epilepsy (moderate level of evidence). In frontal lobe epilepsy, the lateralization of nonversive head turning may vary based on sub-lobar localization, but high-level evidence is lacking. Gyratory seizures are likely contralateral when initiated by versive head turning and evolving into focal-to-bilateral tonic-clonic seizures; in other cases, they may be ipsilateral, particularly in temporal and mesial frontal epilepsy, but the available evidence is insufficient for a definitive conclusion. SIGNIFICANCE: The lateralizing value of ictal head turning depends on its specific characteristics and clinical context.

Indexed as

Epilepsies, PartialFunctional LateralityHead MovementsSeizuresElectroencephalographyHumansepilepsy surgerygyratorynonversiveseizureversive

Identifiers

PMID40407688
PMCPMC12398197

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.