Evidence map›Paper›PMID 40407449›Full record

ArticleJournal of functional morphology and kinesiology2025

Body Composition Benefits Diminish One Year After a Resistance Training Regimen in Breast Cancer Patients, Although Improvements in Strength, Balance, and Mobility Persist.

Colin E Champ, Jared Rosenberg, Chris Peluso, Christie Hilton, Rhyeli Krause, Alexander K Diaz, David J Carpenter

Abstract read
In one paragraph

Article in Journal of functional morphology and kinesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Colin E ChampAllegheny Health Network Cancer Institute, Exercise Oncology & Resiliency Center, Pittsburgh, PA 15202, USA.ORCID 0000-0002-1879-7463
Jared RosenbergDepartment of Exercise Science, SUNY Cortland, Cortland, NY 13045, USA.ORCID 0000-0002-1791-6790
Chris PelusoAllegheny Health Network Cancer Institute, Exercise Oncology & Resiliency Center, Pittsburgh, PA 15202, USA.
Christie HiltonDepartment of Medical Oncology, Allegheny Health Network, Pittsburgh, PA 15202, USA.
Rhyeli KrauseAllegheny Health Network Cancer Institute, Exercise Oncology & Resiliency Center, Pittsburgh, PA 15202, USA.
Alexander K DiazDepartment of Radiation Oncology, Murray-Calloway County Hospital, Murray, KY 42071, USA.
David J CarpenterDepartment of Radiation Oncology, Wellstar Paulding Medical Center, Hiram, GA 30141, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesResistance training can improve body composition and physical function during and after breast cancer treatment and improve quality of life. It is unclear whether these changes persist once a person is no longer actively enrolled in a structured exercise regimen. Thus, we analyzed participants from the EXERT-BC protocol, assessing an intense exercise regimen in women with breast cancer at one year.

methodsAll the participants were asked to undergo reassessment at one year. Current exercise habits, injuries, changes in medical history, body composition, handgrip strength, functional mobility and balance, and patient-reported quality of life were assessed. Pairwise comparison was performed via the paired t test.

resultsOut of 40 initial participants, 33 returned for reevaluation, with 6 lost to follow-up and 1 with unrelated hospitalization. The median age was 57.8 years, and stage at diagnosis was 1. Weekly exercise was reported by 16 participants (48.5%), with 14 of the 16 following structured resistance training. Between completion of the EXERT-BC and one year follow-up, five women (15.2%) experienced musculoskeletal injuries, which inhibited their ability to exercise. Three women (9%), who were no longer exercising experienced orthopedic injuries requiring medical intervention. The significant reduction in percent body fat, total body fat, excess fat, and increases in muscle mass, resting metabolic rate, and whole-body phase angle dissipated at 1 year. Activity levels and quality of life were no longer significantly improved. However, strength, mobility, and balance remained significantly improved versus pre-exercise measurements, whether a participant was still engaged in exercise or not.

conclusionsAfter a 3-month dose-escalated resistance training regimen, exercise compliance was poor at one year. The anthropomorphic benefits of the regimen regressed by one year; however, the improvements in strength, balance, and mobility persisted.

Indexed as

body compositionbreast cancerexercise sciencehypertrophyresistance training

Identifiers

PMID40407449
PMCPMC12101267

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.