Evidence map›Paper›PMID 40407374›Full record

ArticleMicrobiology spectrum2025

Membrane vesicle production via cell-to-cell communication-induced autolysis in

Ryo Nagasawa, Tamami Ito, Chika Yamamoto, Mio Unoki, Nozomu Obana, Nobuhiko Nomura, Masanori Toyofuku

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Membrane Vesicles ImproveMicroorganisms · 2026
    Article
  3. Review
  4. Recent advances in membrane vesicles ofJournal of oral microbiology · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. A brief review of membrane vesicles fromFrontiers in microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryo Nagasawa *Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.ORCID 0000-0002-3106-7916
Tamami Ito *Graduate School of Science and Technology, University of Tsukuba, Tsukuba, Ibaraki, Japan.ORCID 0009-0002-8850-7545
Chika YamamotoGraduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Mio UnokiGraduate School of Science and Technology, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Nozomu ObanaFaculty of Medicine, Transborder Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.ORCID 0000-0002-0637-7904
Nobuhiko NomuraMicrobiology Research Center for Sustainability, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Masanori ToyofukuMicrobiology Research Center for Sustainability, University of Tsukuba, Tsukuba, Ibaraki, Japan.ORCID 0000-0003-4627-9230

Funding

Japan Science and Technology Agency JPMJMI21G8, JPMJGX23B2Japan Society for the Promotion of Science 18J21373Japan Society for the Promotion of Science 23H05471Japan Society for the Promotion of Science 23K26811Japan Society for the Promotion of Science 24KJ0504Suntory Foundation for Life Sciences
6 · The paper itself

Abstract

Membrane vesicles (MVs) released from bacteria into the extracellular environment play various roles in bacterial and bacterial-host interactions. In Gram-positive bacteria, cell wall degradation or damage is crucial for cytoplasmic MV (CMV) release because the cytoplasmic membrane must pass through the thick cell wall to the extracellular space. Although

Indexed as

Extracellular VesiclesStreptococcus mutansBacterial ProteinsBacteriolysisBiofilmsCell CommunicationCell MembraneN-Acetylmuramoyl-L-alanine AmidaseBacterial ProteinsN-Acetylmuramoyl-L-alanine Amidaseautolysiscell-cell communicationmembrane vesicleStreptococcus mutans

Identifiers

PMID40407374
PMCPMC12211075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.