Evidence map›Paper›PMID 40407272›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2025

Long-term home parenteral nutrition in chronic intestinal failure following metabolic and bariatric surgery and its clinical outcomes: A descriptive cohort study.

Dane Christina Daoud, Katherine J P Schwenger, Yasaman Ghorbani, Leah Gramlich, George Ou, David Armstrong, Maitreyi Raman, Johane P Allard, Barbara Bielawska

Abstract read
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dane Christina DaoudDepartment of Medicine, Division of Gastroenterology, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.
Katherine J P SchwengerDepartment of Medicine, Division of Gastroenterology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
Yasaman GhorbaniDepartment of Medicine, Division of Gastroenterology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
Leah GramlichDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.ORCID https://orcid.org/0000-0001-6308-0229
George OuDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
David ArmstrongDivision of Gastroenterology & Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Maitreyi RamanDivision of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-9129-3632
Johane P AllardDepartment of Medicine, Division of Gastroenterology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-8956-7059
Barbara BielawskaDepartment of Medicine, University of Ottawa, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0002-0877-7151

Funding

Ontario Medical Supply (unrestricted grant)
6 · The paper itself

Abstract

backgroundMetabolic and bariatric surgery is one of the most efficacious treatments for obesity. The increasing incidence of referrals to intestinal rehabilitation programs and the necessity for long-term parenteral nutrition because of bariatric surgery complications have gained attention, yet data remain limited. Our objectives were to (1) assess parenteral nutrition-related complication rates of patients requiring long-term parenteral nutrition because of bariatric surgery complications and (2) compare outcomes between types of metabolic and bariatric surgery.

methodsThis was a descriptive cohort (n = 25) study, which gathered data from patients enrolled in the national registry with a history of metabolic and bariatric surgery at baseline and 2 years and included demographics, biochemical parameters, parenteral regimens, line sepsis, hospitalizations, and functional status.

resultsIn this study, 92% were women with a mean age of 53.8 ± 8.6 years. The most prevalent procedure performed was Roux-en-Y gastric bypass (60%). Short bowel syndrome was observed in 40% of our cohort (n = 10). After 2 years, there was a significant reduction in the need for parenteral nutrition compared with baseline, with 37.5% of patients achieving weaning. No significant disparities were observed in the incidence of line sepsis, hospitalizations, or Karnofsky performance status between baseline and the 2-year follow-up, regardless of the type of surgery. Roux-en-Y gastric bypass was associated with lower body mass index at the 2-year mark.

conclusionIn post-metabolic and bariatric surgery patients, long-term parenteral nutrition is well tolerated based on clinical outcomes and functional status is not influenced by the type of surgery.

Indexed as

Bariatric SurgeryIntestinal FailureParenteral Nutrition, HomePostoperative ComplicationsAdultAgedChronic DiseaseCohort StudiesFemaleGastric BypassHumansMaleMiddle AgedSepsisShort Bowel SyndromeTreatment Outcomebariatric surgerychronic intestinal failurehome parenteral nutritionmalnutrition

Identifiers

PMID40407272
PMCPMC12319468

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.