Evidence map›Paper›PMID 40407065›Full record

ArticleJournal of the American Heart Association2025

Infection-Related Hospitalization and Incident Heart Failure in MarketScan: A Case-Crossover Study.

Rebecca L Molinsky, Pamela L Lutsey, Rob F Walker, Wendy Wang, Melana Yuzefpolskaya, Katherine Giorgio, David M Vock, Richard MacLehose, Paolo C Colombo, Ryan T Demmer

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rebecca L MolinskyDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0001-9564-0147
Pamela L LutseyDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0002-1572-1340
Rob F WalkerDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0002-1151-3675
Wendy WangDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0001-6025-0173
Melana YuzefpolskayaDivision of Cardiology, Department of Medicine Columbia University Irving Medical Center New York NY USA.ORCID 0000-0003-4729-8943
Katherine GiorgioDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0002-1815-4732
David M VockDivision of Biostatistics and Health Data Science, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0002-5459-9579
Richard MacLehoseDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.
Paolo C ColomboDivision of Cardiology, Department of Medicine Columbia University Irving Medical Center New York NY USA.ORCID 0000-0003-4977-3285
Ryan T DemmerDivision of Epidemiology, Department of Quantitative Health Sciences Mayo Clinic College of Medicine and Science Rochester MN USA.ORCID 0000-0003-3429-0379

Funding

Improving Reproducibility by Incorporating UncertaintyR01LM013049 · NLM · EMORY UNIVERSITY · PI LASH, TIMOTHY L. · 2019 to 2022
$1.1M
Mentoring and Research in Patient-Oriented Cardiovascular PharmacoepidemiologyK24HL159246 · NHLBI · UNIVERSITY OF MINNESOTA · PI PAMELA L. Lutsey · 2021 to 2026
$644k
NHLBI NIH HHS K24 HL159246NLM NIH HHS R01 LM013049
6 · The paper itself

Abstract

backgroundHeart failure (HF) is a growing public health burden. Systemic inflammation is commonly observed in patients with HF and believed to be related to disease pathogenesis. Infection is a potential acute trigger of chronic inflammation. Our objective was to examine the relationship between infection-related hospitalization (IRH) and HF. METHODS AND

resultsWe studied beneficiaries with at least 15 months of continuous enrollment in the US-based MarketScan databases during 2013 to 2019. We included n=152 008 patients with an inpatient or outpatient HF

conclusionsIRH was associated with incident HF after both 1 and 3 months and may represent a modifiable risk factor for HF.

Indexed as

Heart FailureHospitalizationInfectionsAdultAgedCross-Over StudiesDatabases, FactualFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsUnited Statescase‐crossoverclaims dataheart failureinfection‐related hospitalization

Identifiers

PMID40407065
PMCPMC12229181

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.