Evidence map›Paper›PMID 40407037›Full record

Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2025

No effect of either heat therapy or aerobic exercise training on blood pressure in adults with untreated hypertension: a randomized clinical trial.

Brendan W Kaiser, Lindan N Comrada, Brandon M Gibson, Emma L Reed, Kieran S S Abbotts, Emily A Larson, Madison I Serrano, Karen Wiedenfeld Needham, Christopher L Chapman, John R Halliwill and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brendan W KaiserBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.ORCID 0000-0002-0974-6015
Lindan N ComradaBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.ORCID 0009-0002-1318-0170
Brandon M GibsonBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.
Emma L ReedBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.ORCID 0000-0002-8870-4699
Kieran S S AbbottsBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.ORCID 0000-0001-5451-6369
Emily A LarsonBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.ORCID 0000-0001-9058-6452
Madison I SerranoBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.
Karen Wiedenfeld NeedhamBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.
Christopher L ChapmanBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.ORCID 0000-0001-8251-9356
John R HalliwillBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.ORCID 0000-0003-3001-1715
Christopher T MinsonBowerman Sports Science Center, Department of Human PhysiologyUniversity of Oregon, Eugene, Oregon, United States.ORCID 0000-0003-3459-3708

Funding

Heat Therapy versus Exercise Training in HypertensionR01HL144128 · NHLBI · UNIVERSITY OF OREGON · PI HALLIWILL, JOHN R., MINSON, CHRISTOPHER TODD · 2018 to 2021
$2.6M
Sympathetic Vascular Regulation following Heat Stress in Young and Aged HumansF31HL158087 · NHLBI · UNIVERSITY OF OREGON · PI LARSON, EMILY A · 2021 to 2023
$86k
Exercise vs. Heat Therapy Effects on Kidney Function in Adults with Untreated HypertensionF32HL164021 · NHLBI · UNIVERSITY OF OREGON · PI CHAPMAN, CHRISTOPHER L · 2022 to 2023
$76k
American Heart Association (AHA) 19TP34890033HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) F31HL158087HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) F32HL164021HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL144128NHLBI NIH HHS F31 HL158087NHLBI NIH HHS F32 HL164021NHLBI NIH HHS R01 HL144128University of Oregon Foundation (UO Foundation) Eugene and Clarissa Evonuk Memorial Graduate Fellowship
6 · The paper itself

Abstract

Hypertension, a primary and preventable risk factor for cardiovascular and kidney disease, may be ameliorated by nonpharmacological lifestyle interventions such as aerobic exercise and heat therapy. Although both interventions have been demonstrated to reduce blood pressure in a variety of populations, there are no studies that have directly compared these methods for lowering blood pressure in adults with untreated hypertension. Forty-one adults (48 [35, 56] yr) were randomized to complete either 30 sessions of aerobic exercise training (

Indexed as

Blood PressureExerciseExercise TherapyHypertensionHyperthermia, InducedAdultBlood Pressure Monitoring, AmbulatoryCardiorespiratory FitnessFemaleHot TemperatureHumansMaleMiddle AgedVascular Stiffnessheat therapyhypertension, prevention and controlkidney functionvascular stiffness

Identifiers

PMID40407037
PMCPMC12225054

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.