ArticleCureus2025
Hepatic Cyst Radioiodine Uptake on Whole-Body Scan in Differentiated Thyroid Cancer: Implications for Lesion Characterization and Misdiagnosis Avoidance.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- False-positive and true-positive orbital iodine-131 uptake after radioiodine therapy: two contrasting cases clarified by SPECT/CT.Quantitative imaging in medicine and surgery · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radioactive iodine (RAI) imaging constitutes a fundamental diagnostic tool in post-operative thyroid cancer management. A diverse spectrum of uptake patterns, encompassing both physiological and pathological entities, has been reported in patients undergoing RAI studies. Particularly, a variety of non-thyroidal conditions can present with unusual patterns of RAI uptake in the liver, complicating diagnosis. This case report presents a 51-year-old female with papillary thyroid cancer who underwent a whole-body RAI scan. The study revealed an atypical pattern of increased radiotracer concentration within the liver for which subsequent radiological investigations led to the diagnosis of two liver lesions, one was a simple hepatic cyst and another was most likely to be a hepatic arteriovenous malformation (HAVM) both located in segment VII based on abdominal magnetic resonance imaging (MRI) findings, an unexpected finding that could be mistaken for other differential diagnoses, including metastatic differentiated thyroid cancer (DTC), granulomas, abscesses, hydatid cysts, biliary tract dilatation, and other benign non-thyroidal neoplasia. Recognizing these diverse entities is essential for the accurate interpretation of RAI scans and for avoiding misdiagnosis. This finding may help clinicians avoid misdiagnosing such ancillary observations as metastases, thereby improving diagnostic accuracy in thyroid cancer management.
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