ArticleCureus2025
A Low Level of High-Density Lipoprotein Cholesterol Predicts All-Cause Mortality Within 30 Days in Hospitalized Elderly Patients.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether low levels of high-density lipoprotein cholesterol (HDL-C) in the blood determine mortality has not been fully elucidated among elderly patients. It is thus a particular concern to see the predictive implication of HDL-C for post-hospitalized mortality in an elderly population.
methodsThis study was planned to investigate the HDL-C level at admission to a hospital in 493 patients of ≥70 years of age. The outcome was death from any cause within the first 30 days after admission. Cox proportional hazards models were used for the analyses. In addition, the time-dependent (follow-up period) receiver operating characteristic (ROC) curve analysis of HDL-C was performed for all-cause mortality.
resultsThe median age of patients was 89 years, and the proportion of male patients was 41%. The median HDL-C level at admission was 41 mg/dL. Deaths occurred in 89 patients (18%) during a median follow-up period of 27 days. In a multivariate model, the HDL-C showed a hazard ratio of 0.977 (95% confidence interval (CI) 0.955-0.998). The results of the ROC curve analysis on all-cause mortality demonstrated that the area under the curve value was 0.67 (95% CI 0.60-0.74) and the cut-off value of HDL-C was 31 mg/dL.
conclusionsA low HDL-C level at admission was a predictor of all-cause mortality within 30 days in hospitalized elderly patients. The cut-off value of HDL-C was deemed to be low in considering the reference value in daily practice. When elderly patients are admitted, the HDL-C level could be the focus of attention for the prediction of the prognosis and disease management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.