Evidence map›Paper›PMID 40406774›Full record

ArticleCureus2025

Bone Marrow Metastasis in Non-hematological Malignancies: Data From a Tertiary Care Hospital in North India.

Satish Kumar, Kaushal Kumar, Rawi Agrawal, Vijayanand Choudhary

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Satish KumarDepartment of Hematology, Indira Gandhi Institute of Medical Sciences, Patna, IND.
Kaushal KumarDepartment of Hematology, Indira Gandhi Institute of Medical Sciences, Patna, IND.
Rawi AgrawalDepartment of Hematology, Indira Gandhi Institute of Medical Sciences, Patna, IND.
Vijayanand ChoudharyDepartment of Hematology, Indira Gandhi Institute of Medical Sciences, Patna, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background It is known that the diagnosis of non-hematological malignancy from bone marrow is uncommon. Also, aspiration from the bone marrow is considered one method that aids in the diagnosis of bone metastases. The study examined bone marrow results and a thorough examination of bone marrow in non-hematological cancers that have metastasized to the bone marrow. Materials and methods This was a retrospective study that was conducted at the Department of Hematology, Indira Gandhi Institute of Medical Sciences (IGIMS), Patna, Bihar, India. A total of 200 cases of bone marrow aspiration and 150 cases of bone marrow biopsies with relevant clinical features, hematological, and radiological findings have been enrolled in the study. Ethical clearance has been granted by the Institutional Ethics Committee (IEC) of IGIMS. Results It was observed that 62 (31%) patients with non-hematological malignancies suffered from bone marrow metastases. The population with bone marrow metastases varies, as 50 (80.6%) of the patient population comprised adults, while the pediatric population was 12 (19.4%). Anemia, thrombocytopenia, leukopenia, pancytopenia, and nucleated immature blood cells were some common findings of peripheral blood smears associated with non-hematological malignancies. Conclusion It concluded the necessity of diagnosing bone marrow metastases in patients with non-hematological malignancies. The study could not find any assured predictive parameter for bone marrow metastases. Conditions like anemia, thrombocytopenia, leukopenia, and others have been revealed by examining peripheral blood smears.

Indexed as

bone marrow metastasishematological cancernon-hematological cancernon-hematological malignanciesretrospective study

Identifiers

PMID40406774
PMCPMC12096030

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