Evidence map›Paper›PMID 40406764›Full record

ReviewCureus2025

Efficacy of Osteopathic Manipulative Treatment in Creating a Difference in Pain Levels for Patients With Localized Joint Pain: A Meta-Analysis of Randomized Controlled Trials.

Jason S DeFrancisis, Benjamin M Vinarski, Melany Abreu, Jalal Ibrahim, Robert Hostoffer

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jason S DeFrancisisOrthopedic Surgery, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Benjamin M VinarskiInternal Medicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Melany AbreuPsychiatry, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Jalal IbrahimDermatology, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Robert HostofferAllergy and Immunology, Case Western Reserve University, Cleveland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteopathic manipulative treatment (OMT) is a therapy utilized by osteopathic physicians in diverse clinical environments. Among the many uses, OMT may be used in attempts to relieve pain in patients. Joint pain is among the most common causes of pain, with millions worldwide suffering from joint pain. This meta-analysis examines the efficacy of OMT in creating a difference in pain levels for patients with localized joint pain. This meta-analysis, comprising three studies and 187 patients, found a mean difference in pain between OMT and non-OMT groups using the common effects model to be -3.09 (-3.57; -2.61) with p<0.0001, suggesting that OMT resulted in a significant pain difference in those with joint pain. However, the random effects model showed a mean difference of -1.80 (-7.31; 3.78), which was not statistically significant. Furthermore, the meta-analysis at hand had a heterogeneity measure, known as I

Indexed as

elbow joint painjoint painknee joint painorthopedic interventionorthopedicsosteopathic manipulative medicineosteopathic manipulative treatment (omt)shoulder joint pain

Identifiers

PMID40406764
PMCPMC12097846

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.