ArticleFrontiers in neurology2025
Semiological differences between children and adults with temporal lobe epilepsy: a video-EEG based multivariate analysis.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Neurological Complications After Pediatric Liver and Kidney Transplantation: A Comprehensive Review of Acute Symptomatic Seizures.Pediatric transplantation · 2026Review
- Bitemporal Lobe Epilepsy: Evolving Diagnostic and Treatment Paradigms.Epilepsy currents · 2026Article
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Authors and funding
12 authors.
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Abstract
Objective: This study investigated the differences in semiological characteristics of temporal lobe epilepsy (TLE) between children and adult populations, specifically examining the impact of age on these manifestations. Using multivariate analysis, this study assessed the influence of age on TLE clinical manifestations, including seizure complexity, while controlling for etiology and lesion location. Methods: This study retrospectively analyzed clinical data from patients who underwent anterior temporal lobectomy (ATL) and achieved seizure-free at Sanbo Brain Hospital. Semiological features were analyzed using video-electroencephalogram (video-EEG) recordings. Following descriptive analysis of clinical characteristics and seizure symptom differences between children and adult cohorts, univariate and multivariate logistic regression analyses were performed to evaluate associations between clinical variables and specific seizure components. Results: A total of 176 patients (39 children and 137 adults) who underwent ATL and achieved seizure-free status met the inclusion criteria for this study. Significant differences were observed between children and adults in the incidence of: auras ( Significance: This study demonstrates significant age-dependent differences in semiological manifestations of TLE, suggesting that age-related neurodevelopmental changes underlie distinct seizure patterns. These findings support age-specific treatment strategies, as age affects TLE seizure patterns and clinical management decisions.
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