Evidence map›Paper›PMID 40406683›Full record

ArticleFrontiers in allergy2025

Effect of seasonal exposure in aeroallergen-sensitised patients with irritable bowel syndrome-diarrhoea.

Carlo Maria Rossi, Marco Vincenzo Lenti, Stefania Merli, Martina Fiorita, Antonio Lo Bello, Mario Andrea Latorre, Paola Ilaria Bianchi, Nicola Aronico, Annalisa De Silvestri, Antonio Di Sabatino

Abstract read
In one paragraph

Article in Frontiers in allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carlo Maria Rossi *Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Marco Vincenzo Lenti *Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Stefania MerliFirst Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Martina FioritaDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Antonio Lo BelloDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Mario Andrea LatorreDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Paola Ilaria BianchiFirst Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Nicola AronicoFirst Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Annalisa De SilvestriBiostatistics and Clinical Trial Centre, Fondazione IRCCS San Matteo, Pavia, Italy.
Antonio Di SabatinoDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pollen allergy may influence irritable bowel syndrome (IBS) symptoms; however, available data are scant. Aims: This study aims to assess symptom variability in atopic IBS patients. Methods: We retrospectively analysed consecutive adult IBS patients evaluated between 2021 and 2024. Patients from the overall IBS cohort and the IBS-diarrhoea (IBS-D) subgroup were classified according to their sensitisation into grass-positive, house dust mite (HDM)-positive, or unsensitised. Symptom burden was assessed using the gastrointestinal symptom rating scale (GSRS) and a visual analogue scale for abdominal pain/distension, both outside the season period (T0) and during the pollination season (T1). Results: A total of 61 IBS patients were recruited (median age 34 years, IQR 25-50, F:M ratio 3.6:1), including 38 patients (62.8%) with IBS-D (median age 30 years, IQR 28-47, F:M ratio 2.8:1). Atopy was common in the IBS-D subgroup, particularly with respiratory manifestations. The mean GSRS significantly ( Conclusions: Pollination season influences symptoms in IBS-D patients sensitised to seasonal allergens.

Indexed as

bowelirritable bowel syndromemast cellpollinosisseason

Identifiers

PMID40406683
PMCPMC12095291

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.