Evidence map›Paper›PMID 40406647›Full record

ArticleHealth science reports2025

Assessment of Scoring Balloons in STEMI Patients Treated With DCB-Only Angioplasty: A Single Center Study.

Ioannis Merinopoulos, Natasha Corballis, Tharusha Gunawardena, U Bhalraam, Rajkumar Natarajan, Johannes Reinhold, Upul Wickramarachchi, Clint Maart, Chris Sawh, Sreekumar Sulfi and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04482972, which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04482972 no registry record found
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Safety aspects ofFrontiers in cardiovascular medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ioannis MerinopoulosDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.ORCID https://orcid.org/0000-0002-2059-0357
Natasha CorballisDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Tharusha GunawardenaDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.ORCID https://orcid.org/0000-0003-4456-2649
U BhalraamDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Rajkumar NatarajanDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Johannes ReinholdDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Upul WickramarachchiDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Clint MaartDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Chris SawhDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Sreekumar SulfiDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Tim GilbertDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Trevor WistowDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Alisdair RydingDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Vassilios S VassiliouDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.
Simon C EccleshallDepartment of Cardiology Norfolk and Norwich University Hospital Norwich Norfolk UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: A randomized trial has previously demonstrated that neointimal modification with a scoring balloon improves the anti-restenotic effect of drug-coated balloon (DCB) in patients with drug-eluting stent restenosis. There are very limited data about the safety and efficacy of using scoring balloons as part of lesion preparation in patients with STEMI, especially in patients with de novo disease treated with DCB-only angioplasty. Methods: We undertook an analysis of the SPARTAN Norwich Registry to address this question. We compared the composite endpoint of cardiovascular mortality or unplanned target lesion revascularization in the DCB-only cohort stratified based on the use or not of scoring balloon as part of the lesion preparation. Furthermore, we undertook a propensity score-matched analysis of the DCB-only cohort. Results: A total of 452 consecutive patients were treated with DCB-only angioplasty and scoring balloon was used in 121 patients as part of the lesion preparation. Scoring balloon was not a significant predictor of the composite endpoint even after propensity score-matched analysis. Chronic obstructive pulmonary disease was the only significant predictor of the composite endpoint after propensity score-matched analysis. Conclusion: This is the first study demonstrating the safety and efficacy of scoring balloon as part of lesion preparation in patients with STEMI due to de novo disease treated with DCB-only angioplasty. Trial Registration: https://clinicaltrials.gov/ct2/show/NCT04482972; Unique identifier: NCT04482972.

Indexed as

DCB‐only angioplastyscoring balloonSTEMI

Identifiers

PMID40406647
PMCPMC12095844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.