Evidence map›Paper›PMID 40406550›Full record

ArticleClinical case reports2025

The First Case of a Single-Dose, Intravenous Perampanel Administration for Early Postoperative Seizure Prophylaxis.

Narushi Sugii, Takeshi Yamada, Eiichi Ishikawa

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Narushi SugiiDepartment of Neurosurgery Institute of Medicine, University of Tsukuba Tsukuba Japan.ORCID https://orcid.org/0000-0001-7255-9776
Takeshi YamadaTsukuba Clinical Research and Development Organization University of Tsukuba Tsukuba Japan.
Eiichi IshikawaDepartment of Neurosurgery Institute of Medicine, University of Tsukuba Tsukuba Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early postoperative epileptic seizure (EPS) may occur in neurosurgical patients. Perampanel has an extended serum half-life plus a rapid onset of action. The intravenous form of perampanel was first launched in Japan, and it may be an option for EPS prevention in brain surgery.

Indexed as

early postoperative seizureglioblastomaintravenous drip infusionperampanelprophylaxissingle‐dose

Identifiers

PMID40406550
PMCPMC12096365

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.