Evidence map›Paper›PMID 40406524›Full record

ArticleFrontiers in cellular and infection microbiology2025

Extending the culture duration could not improve the culture positivity rate and clinical outcomes of periprosthetic joint infection.

Baijian Wu, Yuan Lin, Jinhui Su, Lan Lin, Zhenggui Yu, Chaofan Zhang, Xinyu Fang, Zida Huang, Wenming Zhang

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Baijian Wu *Department of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Yuan Lin *Department of Orthopaedic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Jinhui Su *Department of Orthopaedic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Lan Lin *Department of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Zhenggui YuDepartment of Orthopaedic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Chaofan ZhangDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Xinyu FangDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Zida HuangDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Wenming ZhangDepartment of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the clinical value of extending the culture time for accurately diagnosing hip or knee PJI. Methods: This retrospective study included 201 hip or knee PJI patients. All specimens were cultured using a standardized procedure. For all samples collected after January 2022, the extended culture period was 14 to 21 days. The detection accuracy and pathogen distribution of the standard culture duration (7 days) was compared with those extending. Results: The overall culture positivity rate was 89.05% (179/201). The most common pathogens were coagulase-negative staphylococci (CoNS, n=54) and methicillin-resistant Conclusion: Extending the culture time didn't significantly improve the clinical outcomes of PJI, rate of culture positivity or polymicrobial infection detection rate.

Indexed as

Bacteriological TechniquesProsthesis-Related InfectionsAdultAgedAged, 80 and overBacteriaFemaleHumansMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedRetrospective StudiesStaphylococcal InfectionsTime Factorsculture periodhip & knee arthroplastypathogensperiprosthetic joint infectiontime to positivity

Identifiers

PMID40406524
PMCPMC12095319

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.