Evidence map›Paper›PMID 40406511›Full record

ArticleEvidence-based practice in child and adolescent mental health2025

Dialectical Behavior Therapy for Adolescents with Borderline Personality Disorder: Emotion Dysregulation, Abuse, and Treatment Outcomes.

Nathaniel P Shogren, Julianne Wilner Tirpak, Nicole P Porter, Cynthia Kaplan, Blake Ronzio, Josephine S Au, Alan E Fruzzetti

Abstract read
In one paragraph

Article in Evidence-based practice in child and adolescent mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nathaniel P ShogrenMcLean Hospital and Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.
Julianne Wilner TirpakMcLean Hospital and Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.
Nicole P PorterMcLean Hospital and Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.
Cynthia KaplanMcLean Hospital and Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.
Blake RonzioMcLean Hospital and Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.
Josephine S AuMcLean Hospital and Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.
Alan E FruzzettiMcLean Hospital and Department of Psychiatry, Harvard Medical School, Belmont, MA, USA.

Funding

Examination of Reward Processing in the Treatment of Adolescent Major DepressionK23MH097786 · NIMH · MCLEAN HOSPITAL · PI AUERBACH, RANDY PATRICK · 2013 to 2016
$686k
NIMH NIH HHS K23 MH097786
6 · The paper itself

Abstract

Objective: Borderline Personality Disorder (BPD) is characterized by extreme emotional dysregulation. Dialectical Behavioral Therapy (DBT) is an empirically supported and effective treatment for BPD in adolescents and adults. However, the extent to which exposure to childhood abuse (i.e. physical and sexual abuse) impacts treatment outcomes is not well understood. This open trial investigated the effectiveness of an intensive residential DBT program in reducing emotion dysregulation in adolescents with BPD symptoms, as well as the impact that severity and type of childhood abuse had on treatment outcomes. Method: Participants (N = 46) were female-identifying adolescents 13 to 20 years of age enrolled in an intensive residential DBT treatment program. Severity of abuse exposure and abuse subtype (Childhood Trauma Questionnaire, Short Form (CTQ-SF), and difficulties with emotional dysregulation (DERS) were assessed at admission and DERS again after one month of treatment. Results: Bivariate correlation between DERS Total Score and Abuse Exposure Total Score indicated that severity of abuse exposure had a medium positive association with emotion dysregulation at admission. Mixed model ANOVA results showed significant reductions in emotion dysregulation following one month of treatment, with a large effect size. Exploratory analysis testing exposure to different subtypes of childhood abuse as a moderator of treatment effects was non-significant. Conclusions: Emotion dysregulation showed significant reductions following intensive residential DBT interventions. Reductions were consistent across subtypes of abuse exposure. Implications for the treatment of adolescents with abuse histories and current BPD-related problems, and the relationship between child abuse exposure and emotion dysregulation overall, are discussed.

Indexed as

AdolescentsBorderline Personality DisorderChild AbuseDialectical Behavior TherapyEmotion Dysregulation

Identifiers

PMID40406511
PMCPMC12094097

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.