ArticleFrontiers in aging2025
Menopause-related changes to maxillary trabecular bone micro-architecture.
Article in Frontiers in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Inflammaging in periodontal, periapical, and malignancy-associated disease: drivers of alveolar bone loss and repair.Journal of bone and mineral metabolism · 2026Review
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Authors and funding
5 authors.
Funding
Abstract
The number of midlife women seeking orthodontic treatment has significantly increased over the past 40 years. With this rise, orthodontists need to consider the potential impact of menopause on treatment planning. There have been no recent published studies on maxillary trabecular bone changes in humans related to menopause. This study aimed to explore the subject further. This cross-sectional cohort study was composed of qualifying participants with diagnostic maxillary CBCT images who were separated by self report into pre- (N = 21) and postmenopausal (N = 19) groups. The regions of interest were the trabecular bone of the incisive foramen and maxillary tuberosity. All scans were converted into binary images in order to draw all parametric and ratio raw data. The parameters of interest included trabecular bone volume fraction (BVF), trabecular thickness, trabecular number, and trabecular separation. In the incisive foramen subgroup, postmenopausal women showed a significant increase in trabecular separation (0.60 ± 0.25 to 0.84 ± 0.31 mm, P < 0.06). For the maxillary tuberosity subgroup, significant decreases in BV/TV (32.58 ± 15.85 to 17.63 ± 14.38 %, P <0.004), trabecular bone surface/tissue volume (2.66 ± 1.01 to 1.43 ± 1.09 %, P < 0.001) and trabecular separation (0.91 ± 0.39 to 1.58 ± 0.51 mm, P < 0.001) were observed. The findings reveal statistically significant differences in maxillary bone density at the level of the maxillary tuberosity and incisive foramen demonstrated in women who are of preversus post-menopausal status.
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