Evidence map›Paper›PMID 40406375›Full record

ArticleCurrent addiction reports2021

Lost in Translation: the Gap Between Neurobiological Mechanisms and Psychosocial Treatment Research for Substance Use Disorders.

Elizabeth D Reese, Louisa F Kane, Catherine E Paquette, Flavio Frohlich, Stacey B Daughters

2 registry-linked trialsAbstract read
In one paragraph

Article in Current addiction reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05845164 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Impulsivity Mediation Using Transcranial Direct Current Stimulation Paired With Acceptance Commitment Therapy as an Adjunctive Therapy for Substance Use Disorder

TypeinterventionalSponsorUniversity of ArizonaRan2023 to 2023Enrolled30ConditionsSubstance Use Disorders, Substance Abuse, Substance UseArmstDCS, tDCS Sham
NCT05863494 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Toward Personalized Treatment of Chronic Pain Using Transcranial Direct Current Stimulation Paired With Deep Learning

TypeinterventionalSponsorUniversity of ArizonaRan2023 to 2023Enrolled40ConditionsChronic PainArmsTranscranial Direct Current Stimulation (tDCS), Transcranial Direct Current Stimulation (tDCS) sham
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth D ReeseDepartment of Psychology and Neuroscience, University of North Carolina, 253 Davie Hall, 235 E. Cameron Ave, Chapel Hill, NC, USA.
Louisa F KaneDepartment of Psychology and Neuroscience, University of North Carolina, 253 Davie Hall, 235 E. Cameron Ave, Chapel Hill, NC, USA.
Catherine E PaquetteDepartment of Psychology and Neuroscience, University of North Carolina, 253 Davie Hall, 235 E. Cameron Ave, Chapel Hill, NC, USA.
Flavio FrohlichDepartment of Psychology and Neuroscience, University of North Carolina, 253 Davie Hall, 235 E. Cameron Ave, Chapel Hill, NC, USA.
Stacey B DaughtersDepartment of Psychology and Neuroscience, University of North Carolina, 253 Davie Hall, 235 E. Cameron Ave, Chapel Hill, NC, USA.

Funding

Technology Enhanced Behavioral Activation Treatment for Substance UseR01DA026424 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAUGHTERS, STACEY B · 2010 to 2019
$4.4M
NIDA NIH HHS R01 DA026424
6 · The paper itself

Abstract

Purpose of Review: To provide an overview of the state of translational substance use disorder (SUD) research by evaluating the extent to which psychosocial interventions target neurobiological processes known to contribute to the maintenance of SUD. Recent Findings: A limited number of studies have investigated neurobiological mechanisms of action for commonly utilized SUD treatment approaches. Restrictive samples, post-treatment-only designs, and failure to include substance use outcomes significantly limit the interpretation of these findings. Summary: Much work is needed to bridge the translational gap between neuroscience and psychosocial treatment research for SUD. Despite existing gaps, addiction neuroscience is highly relevant to SUD assessment, case conceptualization, and treatment. Implications are discussed in addition to suggestions for future research.

Indexed as

AddictionNeurosciencePsychosocial treatmentSubstance use disorderTranslational researchTreatment mechanisms

Identifiers

PMID40406375
PMCPMC12097766

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.