ReviewJournal of Indian Association of Pediatric Surgeons
Efficacy and Safety of Common Salt and other Topical Agents in the Treatment of Umbilical Granuloma in Neonates and Infants: A Systematic Review and Meta-analysis.
Review in Journal of Indian Association of Pediatric Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinical analysis of 25 cases of infant umbilical granuloma treated with topical application of common salt granules.Frontiers in pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Umbilical granuloma (UG) is an occasional sequel after umbilical cord separation in neonates with an incidence of 0.2% to 3.01% of live births. It is characterized by moist, fleshy tissue at the umbilicus and presents as umbilical discharge, redness or frank infection. Treatment options include topical application of silver nitrate, copper sulphate, steroids, and common salt. Silver nitrate, though effective, can cause skin burns and needs caution. Common salt is popular as it is cheap, easily available and relatively safe. In this meta-analysis, we intend to compare the efficacy and safety of common salt with other topical agents for treating umbilical granuloma in neonates and infants. This meta-analysis was done as per the PRISMA guidelines and randomized controlled trials (RCTs) comparing common salt with other topical agents were included. Databases like Cochrane, MEDLINE and Scopus were searched. Data was extracted by two independent reviewers and analysed using RevMan software. Outcomes measured were resolution of UG after application and adverse effects of treatment. We observed that common salt is effective and safe for treatment of umbilical granuloma and has a similar success rate when compared to other topical agents. There are no significant adverse effects with its use. It can even be safely applied by caregivers at home.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.