ArticleChemical science2025
Introduction of flavin anions into photoredox catalysis: acid-base equilibria of lumichrome allow photoreductions with an anion of an elusive 10-unsubstituted isoalloxazine.
Article in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Toward Relative Redox Potential Predictions in Flavoproteins: Treatment of a Charge-Changing Mutation in Alchemical Free Energy Simulations.Journal of chemical theory and computation · 2026Article
- Photophysical properties and acid-base equilibria of lumichrome anions in nonaqueous media.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- Article
- Get a better glimpse on sequential photoreactions of trisnorbornadienes withBeilstein journal of organic chemistry · 2026Article
- Deazaalloxazines - Flavin Derivatives That Provide Reductive Photoredox Catalysis with Inert Substrates.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
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Authors and funding
11 authors.
Funding
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Abstract
Flavins have been established as effective catalysts in oxidative photoredox catalysis. Conversely, their use in reductive photocatalysis remains limited, mainly due to the relatively low stability of the transient flavin radicals (semiquinones), which are used in photoreductions. The fully reduced forms of flavins are also disadvantaged in photocatalysis because they absorb light in the UV rather than in the visible region. In this work, we present a new approach for reductive flavin photocatalysis that utilises a flavin (isoalloxazine) anion derived from the elusive 10-unsubstituted 3,7,8-trimethylisoalloxazine, an unstable tautomer of 3-methyllumichrome. We found the conditions under which this isoalloxazine anion is formed by
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