ArticleFrontiers in nutrition2025
Prognostic nutritional index negative associated with mortality in older Japanese patients with dysphagia.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Clinical Predictors of Worsening in Non-severe Acute Cholangitis.Internal medicine (Tokyo, Japan) · 2026Article
- Article
- Neurological Severity Versus Biomarker Dynamics in Post-Stroke Dysphagia: A Dual-Pathway Model for Functional Recovery and Feeding Transition.Journal of clinical medicine · 2026Article
- Longitudinal trajectories of nutritional markers in patients with de novo Stage IV gastric cancer: a descriptive analysis using one-year survival as a reference.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Day-7 caloric intake as an early dynamic prognostic marker for subsequent mortality in older patients with dysphagia: a landmark cohort analysis.Frontiers in nutrition · 2026Article
- Prognostic value of the lymphocyte-to-C-reactive protein ratio for mortality in geriatric patients with severe dysphagia requiring artificial nutrition: a retrospective secondary analysis.Frontiers in medicine · 2026Article
- Risk Factors for Complications and 90-Day Mortality After Percutaneous Endoscopic Gastrostomy: The Role of Nutritional and Inflammatory Markers.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- Albumin-related nutritional indices and all-cause and cause-specific mortality in older adults with severe dysphagia receiving artificial feeding.Frontiers in nutrition · 2025Article
- Association between controlling nutritional status score and mortality in older patients with dysphagia in Japan:Frontiers in nutrition · 2025Article
- Association between the C-reactive protein-albumin-lymphocyte (CALLY) index and mortality in elderly patients with dysphagia requiring nutritional support.Frontiers in neurology · 2025Article
- Association of the lymphocyte-to-C-reactive protein ratio with long-term mortality in hospitalized older adults with severe dysphagia.Frontiers in nutrition · 2025Article
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2 authors.
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Abstract
Background: The prognostic nutritional index (PNI) has been proven to represent a biomarker for predicting prognosis in many groups of patients with severe diseases. However, few studies have investigated the association between PNI and mortality in Japan older people with dysphagia patients. Objective: This retrospective cohort study aimed to assess the prognostic value of PNI in older Japanese patients with dysphagia. Methods: We analyzed data from 248 patients diagnosed with dysphagia at a single center between January 2014 and January 2017. According to PNI score, all patients were divided into normal nutrition group (PNI ≥ 38), moderate malnutrition group (35 ≤ PNI < 38) and severe malnutrition group (PNI < 35). Cox regression analysis was used to compare the mortality rates among the three groups. Subgroup analyses were conducted, and Kaplan-Meier curves were used to determine the median survival times. Results: The mean age of the patients was 83.0 ± 9.3 years, with a male-to-female ratio of 0.64:1. Of the patients, 180 received percutaneous endoscopic gastrostomy (PEG) and 68 received total parenteral nutrition (TPN). After adjusting for all covariates, the multivariable Cox regression analysis revealed a significant association between PNI and the risk of mortality (HR = 0.94, 95% CI: 0.92-0.97, Conclusion: PNI was negatively associated with mortality in older Japanese patients with dysphagia. There was no interaction for the subgroup analysis. The result was stable.
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