Evidence map›Paper›PMID 40406104›Full record

ReviewFrontiers in immunology2025

MHC-I pathway disruption by viruses: insights into immune evasion and vaccine design for animals.

Yanan Wu, Zhuoya Sun, Lu Xia, Panpan Tian, Liuyang Jiao, Yanze Li, Zhanyong Wei, Xuannian Wang, Xiaoying Li, Gaiping Zhang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yanan WuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Zhuoya SunCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Lu XiaCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Panpan TianCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Liuyang JiaoCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Yanze LiCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Zhanyong WeiCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Xuannian WangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Xiaoying LiCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.
Gaiping ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among various pathogens, viruses pose significant threats to the livestock and poultry industry, resulting in substantial annual costs due to production losses and vaccination. The MHC-I presentation pathway is a crucial surveillance mechanism for preventing viral infections. Consequently, many viruses have evolved sophisticated strategies to inhibit the presentation of viral peptides by MHC-I to CD8

Indexed as

Histocompatibility Antigens Class IImmune EvasionViral VaccinesVirus DiseasesVirusesAnimalsAntigen PresentationHumansLivestockVaccine DevelopmentHistocompatibility Antigens Class IViral Vaccinesadaptive immune responsesimmune evasionMHC-IMHC-I assemblyMHC-I expressionMHC-I transport

Identifiers

PMID40406104
PMCPMC12095009

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.